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Steroid use in kidney transplant recipients presented with acute myocardial infarction     
Yazarlar
Ozgur Ulas Ozcan
Sadi Gulec
Dr. Öğr. Üyesi Eren GÜRSOY Dr. Öğr. Üyesi Eren GÜRSOY
Türkiye
Zeynep Kendi Celebi
Cetin Erol
Özet
Suppression of the hypothalamic-pituitary-adrenal axis due to chronic exogenous steroid use is the most common cause of secondary adrenal insufficiency. Most kidney transplant recipients receive steroid therapy for immunosuppression; they are also at high risk for acute coronary events which can increase their physiological stress. Use of steroids early in the course of acute myocardial infarction (MI) raises concerns about the possibility of an increased risk of aneurysm formation and myocardial rupture. We present six case reports of kidney transplant recipients. Two of these recipients developed adrenal insufficiency after acute anterior MI; the life-threatening situation was successfully managed with corticosteroid administration. Four of these kidney transplant recipients presented with acute anterior MI; in these patients prophylactic steroid therapy prevented adrenal insufficiency, without any complication of the MI. We recommend the use of prophylactic corticosteroids for kidney transplant recipients to prevent adrenal insufficiency in the early course of acute MI. © 2014 Elsevier Inc.
Anahtar Kelimeler
Adrenal insufficiency | Methylprednisolone | Myocardial infarction | Renal transplantation | Steroid
Makale Türü Diğer (Teknik, not, yorum, vaka takdimi, editöre mektup, özet, kitap krıtiği, araştırma notu, bilirkişi raporu ve benzeri)
Makale Alt Türü SCI, SSCI, AHCI, SCI-Exp dergilerinde yayımlanan teknik not, editöre mektup, tartışma, vaka takdimi ve özet türünden makale
Dergi Adı HEART & LUNG
Dergi ISSN 0147-9563
Dergi Tarandığı Indeksler SCI-Expanded
Makale Dili İngilizce
Basım Tarihi 07-2014
Cilt No 43
Sayı 4
Sayfalar 289 / 291
Doi Numarası 10.1016/j.hrtlng.2014.04.006
Makale Linki https://linkinghub.elsevier.com/retrieve/pii/S0147956314001149