| Yazarlar |
Gaffari Türk
Fırat Üniversitesi, Türkiye |
|
Mustafa Sönmez
Fırat Üniversitesi, Türkiye |
|
Muhterem Aydın
Fırat Üniversitesi, Türkiye |
|
Abdurrauf Yüce
Fırat Üniversitesi, Türkiye |
|
Seyfettin Gür
Fırat Üniversitesi, Türkiye |
|
Murat Yüksel
Cumhuriyet Üniversitesi, Türkiye |
Doç. Dr. Emrah Hicazi AKSU
Türkiye |
|
Hakan Aksoy
|
| Özet |
| Background & aim: Pomegranate fruit is inescapably linked with fertility, birth and eternal life because of its many seeds. The aim of this study was to investigate the effects of pomegranate juice (PJ) consumption on sperm quality, spermatogenic cell density, antioxidant activity and testosterone level of male healthy rats. Methods: Twenty-eight healthy adult male Wistar rats were divided into four groups; each group containing seven rats. One milliliter distilled water, 0.25 mL PJ plus 0.75 mL distilled water, 0.50 mL PJ plus 0.50 mL distilled water and 1 mL PJ were given daily for seven weeks by gavage to rats in the first, second, third and fourth groups, respectively. Body and reproductive organ weights, spermatogenic cell density, sperm characteristics, levels of antioxidant vitamins, testosterone, and lipid peroxidation and, antioxidant enzyme activities were investigated. All analyses were done only once at the end of the seven week study period. Data were compared by analysis of variance (ANOVA) and the degree of significance was set at P < 0.05. Results: A significant decrease in malondialdehyde (MDA) level and marked increases in glutathione (GSH), glutathione peroxidase (GSH-Px) and catalase (CAT) activities, and vitamin C level were observed in rats treated with different doses of PJ. PJ consumption provided an increase in epididymal sperm concentration, sperm motility, spermatogenic cell density and diameter of seminiferous tubules and germinal cell layer thickness, and it decreased abnormal sperm rate when compared to the control group. Conclusion: The results suggest that PJ consumption improves sperm quality and antioxidant activity of rats. © 2007 Elsevier Ltd and European Society for Clinical Nutrition and Metabolism. |
| Anahtar Kelimeler |
| Antioxidant enzymes | Lipid peroxidation | Pomegranate juice | Sperm characteristics | Spermatogenic cell density | Testosterone |
| Makale Türü | Özgün Makale |
| Makale Alt Türü | SSCI, AHCI, SCI, SCI-Exp dergilerinde yayımlanan tam makale |
| Dergi Adı | CLINICAL NUTRITION |
| Dergi ISSN | 0261-5614 |
| Dergi Tarandığı Indeksler | SCI |
| Makale Dili | İngilizce |
| Basım Tarihi | 04-2008 |
| Cilt No | 27 |
| Sayı | 2 |
| Sayfalar | 289 / 296 |
| Doi Numarası | 10.1016/j.clnu.2007.12.006 |
| Makale Linki | http://linkinghub.elsevier.com/retrieve/pii/S0261561407002075 |
| Atıf Sayıları | |
| WoS | 146 |
| SCOPUS | 186 |
