The prognostic value of white blood cell count to mean platelet volume ratio in patients with acute coronary syndrome
 
Yazarlar (3)
Murat Yuksel Dicle University, Faculty Of Medicine, Türkiye
Prof. Dr. Abdulkadir YILDIZ Dicle University, Faculty Of Medicine, Türkiye
Murat Cayli Dicle University, Faculty Of Medicine, Türkiye
Makale Türü Açık Erişim Diğer (Teknik, not, yorum, vaka takdimi, editöre mektup, özet, kitap krıtiği, araştırma notu, bilirkişi raporu ve benzeri) (SCI, SSCI, AHCI, SCI-Exp dergilerinde yayınlanan teknik not, editöre mektup, tartışma, vaka takdimi ve özet türünden makale)
Dergi Adı Cardiology Journal (Q3)
Dergi ISSN 1897-5593 Dergi Bilgileri (2015)
Dergi Tarandığı Indeksler SCI-Expanded
Makale Dili İngilizce Basım Tarihi 06-2015
Kabul Tarihi Yayınlanma Tarihi 19-06-2015
Cilt / Sayı / Sayfa 22 / 3 / 351–352 DOI 10.5603/CJ.2015.0029
Makale Linki http://czasopisma.viamedica.pl/cj/article/view/41468
UAK Araştırma Alanları
Kardiyoloji
Özet
We have read the article entitled “White blood cell count to mean platelet volume ratio as a novel non-invasive marker predicting long-term outcomes in patients with non-ST elevation acute coronary syndrome”[1] with great interest. Both leukocytes and platelets have been reported to be involved in several cardiovascular (CV) diseases through inflammatory pathways. The close relationship between inflammation, aggregation, and atherosclerosis progression has become a field of intensive research. The study by Dehghani et al.[1] evaluated the predictive role of white blood cell count/mean platelet volume (WBC/MPV) ratio (WMR) in long-term outcomes of acute coronary syndrome (ACS) patients. However, we have some comments regarding the presented study. Previous studies revealed an association between higher rates of major adverse cardiac events and poorer outcomes with both higher platelet and lower lymphocyte counts [2–4]. The advantage of the platelet-to-lymphocyte ratio (PLR) is that it reflects both hyperactive aggregation and inflammatory pathways, and it may be superior to either the individual platelet or the lymphocyte counts in the prediction of long-term outcome in CV diseases. Azab et al.[5] showed that higher PLR values are associated with higher long-term mortality in patients presenting with non-ST segment elevation ACS. Several additional studies have appeared recently, that integrate the predictive risk of this novel marker, PLR, in ACS settings [6–9]. As increased platelet count and decreased lymphocyte levels are associated with poor CV outcome, it is logical to integrate these 2 parameters into 1. White blood …
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