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Association between the neutrophil to lymphocyte ratio and prehypertension     
Yazarlar
Mesut Aydın
Murat Yüksel
Prof. Dr. Abdulkadir YILDIZ
Türkiye
Nihat Polat
Mehmet Zihni Bilik
Mehmet Ata Akıl
Halit Acet
Muhammed Demir
Ümit İnci
Nizamettin Toprak
Özet
OBJECTIVES: To explore the neutrophil-lymphocyte ratio (NLR) in patients with prehypertension (PHT). BACKGROUND: Inflammation plays an important role in the development of cardiovascular diseases. A pathophysiological link also exists between inflammation and PHT. NLR is a simple marker for the assessment of inflammatory status. There is a lack of data regarding the association between NLR and pre-hypertensive state. METHODS: The present cross-sectional study included 33 newly diagnosed PHT patients and 35 normotensive control subjects. Prehypertension was defined as a systolic blood pressure (BP) of 120-139 mm Hg and/or a diastolic BP of 80-89 mm Hg. RESULTS: Patients were divided into tertiles based on NLR values: 1.17 (0.9-1.42) in tertile 1; 1.57 (1.43-1.78) in tertile 2; and 2.40 (1.82-4.5) in tertile 3. The frequency of PHT was significantly higher for patients in the upper NLR tertile compared to the middle and lower NLR tertiles (21 (91.3 %), 7 (30.4 %), and 5 (22.7 %), respectively; p < 0.001). Systolic BP and diastolic BP were significantly higher among patients in the upper NLR tertile than among those in the other NLR tertiles. CONCLUSION: An association exists between PHT and NLR. NLR measurement, as well as monocyte count, may be used to indicate increased risk of prehypertension (Tab. 2, Ref. 48).
Anahtar Kelimeler
Inflammatory | Neutrophil-to-lymphocyte ratio | Prehypertension
Makale Türü Özgün Makale
Makale Alt Türü SSCI, AHCI, SCI, SCI-Exp dergilerinde yayımlanan tam makale
Dergi Adı Bratislava Medical Journal
Dergi ISSN 1336-0345
Dergi Tarandığı Indeksler SCI-Expanded
Makale Dili İngilizce
Basım Tarihi 01-2015
Cilt No 116
Sayı 8
Sayfalar 475 / 479
Doi Numarası 10.4149/BLL_2015_090
Makale Linki http://www.elis.sk/index.php?page=shop.product_detailsflypage=flypage.tplproduct_id=4360category_id=118option=com_virtuemart
BM Sürdürülebilir Kalkınma Amaçları
Atıf Sayıları
SCOPUS 8
Association between the neutrophil to lymphocyte ratio and prehypertension

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