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Apelin Levels In Isolated Coronary Artery Ectasia    
Yazarlar
Mehmet Zihni Bilik
İbrahim Kaplan
Prof. Dr. Abdulkadir YILDIZ
Türkiye
Mehmet Ata Akıl
Halit Acet
Murat Yüksel
Nihat Polat
Mesut Aydın
Mustafa Oylumlu
Faruk Ertaş
Hasan Kaya
Sait Alan
Özet
The etiopathogenesis of coronary artery ectasia (CAE) is not known completely. In most of the cases, CAE is associated with atherosclerosis; however, isolated CAE has a nonatherosclerotic mechanism. The association between atherosclerotic coronary artery disease and apelin has been examined in previous studies. However, the role of plasma apelin in isolated coronary artery ectasia has not been studied. In this study, we investigated the relationship between plasma apelin levels and isolated coronary artery ectasia. The study population included a total of 54 patients. Twenty-six patients had isolated CAE (53.6±8.1 years); 28 patients with normal coronary arteries (51.6±8.8 years) and with similar risk factors and demographic characteristics served as the control group. Apelin levels were measured using an enzyme-linked immunoassay kit. Apelin level in the CAE group was significantly lower (apelin=0.181±0.159 ng/mL) than that in the control group (apelin=0.646±0.578 ng/mL) (p=0.033). Glucose, creatinine, total cholesterol, triglyceride, low density lipoprotein cholesterol, and high density lipoprotein cholesterol levels were not significantly different between the two groups. In this study, we showed that patients with isolated CAE have decreased plasma apelin levels compared with the control group. Based on the data, a relationship between plasma apelin and isolated CAE was determined.
Anahtar Kelimeler
Apelin protein, human | Coronary artery disease | Dilatation, pathologic | Inflammation
Makale Türü Özgün Makale
Makale Alt Türü SSCI, AHCI, SCI, SCI-Exp dergilerinde yayımlanan tam makale
Dergi Adı KOREAN CIRCULATION JOURNAL
Dergi ISSN 1738-5520
Dergi Tarandığı Indeksler SCI-Expanded
Makale Dili İngilizce
Basım Tarihi 09-2015
Cilt No 45
Sayı 5
Sayfalar 386 / 390
Doi Numarası 10.4070/kcj.2015.45.5.386
Makale Linki https://e-kcj.org/DOIx.php?id=10.4070/kcj.2015.45.5.386
BM Sürdürülebilir Kalkınma Amaçları
Atıf Sayıları
WoS 7
Apelin Levels In Isolated Coronary Artery Ectasia

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