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The relationship between fragmented QRS and functional significance of coronary lesions      
Yazarlar
Ahmet Korkmaz
Prof. Dr. Abdulkadir YILDIZ
Türkiye
Mevlut Demir
Ozyazgan Burcu
Ekrem Sahan
Burak Acar
Umit Guray
Mehmet Ileri
Ozgul Ucar Elalmis
Özet
Background Recently fragmented QRS (fQRS) on electrocardiography (ECG) has been introduced as a predictor of myocardial scarring and myocardial ischemia in coronary artery disease (CAD). Objective The aim of this study was to investigate the relationship between fQRS and fractional flow reserve (FFR) results in patients with the intermediate degree of coronary artery stenosis. Methods A total of 301 consecutive patients who underwent coronary angiography (CAG) and FFR measurement for intermediate coronary artery stenosis were included in the study. The study patients were divided into two groups: the low FFR group (FFR value of ≤0.80) and normal FFR (FFR value of >0.80) group. Both groups were compared in terms of the presence of fQRS. Results Of 301 patients, fQRS was detected in 128 (42.5%) and low FFR was detected in 115 (38.2%). In the low FFR group, fQRS was significantly higher (P < 0.001). Multivariate analysis showed that fQRS was an independent predictor of myocardial ischemia in patients with intermediate coronary stenosis (OR = 7.202, CI 95%, 4.195–12.367; p < 0.001). The presence of fQRS had 70% sensitivity and 74% specificity for the prediction of FFR ≤ 0.80. Conclusion In clinical practice, the presence of fQRS on ECG is associated with myocardial ischemia in patients with intermediate coronary stenosis.
Anahtar Kelimeler
Fragmented QRS,Fractional flow reserve,Ischemia,Coronary artery stenosis
Makale Türü Özgün Makale
Makale Alt Türü SSCI, AHCI, SCI, SCI-Exp dergilerinde yayımlanan tam makale
Dergi Adı Journal of Electrocardiology
Dergi ISSN 0022-0736
Dergi Tarandığı Indeksler SCI-Expanded
Makale Dili İngilizce
Basım Tarihi 05-2017
Cilt No 50
Sayı 3
Sayfalar 282 / 286
Doi Numarası 10.1016/j.jelectrocard.2017.01.005
Makale Linki https://linkinghub.elsevier.com/retrieve/pii/S0022073617300080