Platelet-to-lymphocyte ratio is a predictor of in-hospital mortality patients with acute coronary syndrome
Yazarlar (10)
Mustafa Oylumlu Dicle Üniversitesi, Türkiye
Prof. Dr. Abdulkadir YILDIZ Dicle Üniversitesi, Türkiye
Muhammed Oylumlu Dumlupinar Üniversitesi, Türkiye
Murat Yüksel Dicle Üniversitesi, Türkiye
Nihat Polat Dicle Üniversitesi, Türkiye
Mehmet Zihni Bilik Dicle Üniversitesi, Türkiye
Abdurrahman Akyuz Dicle Üniversitesi, Türkiye
Mesut Aydın Dicle Üniversitesi, Türkiye
Halit Acet Dicle Üniversitesi, Türkiye
Serdar Soydinc Dicle Üniversitesi, Türkiye
| Makale Türü |
Özgün Makale
(SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale)
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| Dergi Adı | Anadolu Kardiyoloji Dergisi | ||
| Dergi ISSN | 1302-8723 | ||
| Dergi Tarandığı Indeksler | SCI-Expanded | ||
| Makale Dili | İngilizce | Basım Tarihi | 04-2015 |
| Cilt / Sayı / Sayfa | 15 / 4 / 277–283 | DOI | 10.5152/akd.2014.5366 |
| Makale Linki | https://www.journalagent.com/anatoljcardiol/pdfs/AnatolJCardiol_15_4_277_283.pdf | ||
| Özet |
| Objective: Platelets and inflammatory cells are vital elements of acute coronary syndromes (ACS). Recent studies have shown that the plateletto- lymphocyte ratio (PLR) is associated with several malignancies; however, there are not enough data in cardiovascular diseases. Therefore, the aim of this study was to explore the association between PLR and in-hospital mortality in patients with ACS. Methods: We retrospectively collected patients with ACS undergoing coronary angiography. Total and differential leukocyte counts were measured by an automated hematology analyzer. Results: This study is single-centered and observational. In total, 587 patients with a mean age of 61.8±13.1 years (68.4% male) were enrolled in the study. Patients were divided into 3 tertiles based on PLR levels. In-hospital mortality was significantly higher among patients in the upper PLR tertile when compared with the middle and lower PLR tertile groups [29 (14.8%) vs. 17 (8.7%) and 2 (1.0%); p<0.001]. In the multiple logistic regression analysis, a high level of PLR was an independent predictor of in-hospital mortality, together with age, total leukocyte count, and creatinine. Using a cutoff point of 142, the PLR predicted in-hospital mortality with a sensitivity of 69% and specificity of 63%. Conclusion: Different from other inflammatory markers and assays, PLR is an inexpensive and readily available biomarker that may be useful for cardiac risk stratification in patients with ACS. |
| Anahtar Kelimeler |
| Acute coronary syndrome | Coronary heart disease | Mortality | Platelet-to-lymphocyte ratio |
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| Web of Science | 57 |
| Scopus | 62 |