Novel markers of endothelial dysfunction and inflammation in Behçet’s disease patients with ocular involvement: epicardial fat thickness, carotid intima media thickness, serum ADMA level, and neutrophil-to-lymphocyte ratio
Yazarlar (9)
Doç. Dr. Murat Yüksel Dicle University, Faculty Of Medicine, Türkiye
Prof. Dr. Abdulkadir YILDIZ Dicle Üniversitesi, Türkiye
Prof. Dr. Mustafa Oylumlu Dicle University, Faculty Of Medicine, Türkiye
Fatih Mehmet Turkcu Dicle University, Faculty Of Medicine, Türkiye
Prof. Dr. Mehmet Zihni Bilik Dicle University, Faculty Of Medicine, Türkiye
Aysun Ekinci Dicle University, Faculty Of Medicine, Türkiye
Bilal Elbey Dicle University, Faculty Of Medicine, Türkiye
Ebru Tekbas Dicle University, Faculty Of Medicine, Türkiye
Sait Alan
Dicle University, Faculty Of Medicine, Türkiye
Dicle University, Faculty Of Medicine, Türkiye
| Makale Türü |
Özgün Makale
(SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale)
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| Dergi Adı | Clinical Rheumatology (Q3) | ||
| Dergi ISSN | 0770-3198 Dergi Bilgileri (2016) | ||
| Dergi Tarandığı Indeksler | SCI-Expanded | ||
| Makale Dili | İngilizce | Basım Tarihi | 03-2016 |
| Kabul Tarihi | – | Yayınlanma Tarihi | 07-03-2015 |
| Cilt / Sayı / Sayfa | 35 / 3 / 701–708 | DOI | 10.1007/s10067-015-2907-0 |
| Makale Linki | http://link.springer.com/10.1007/s10067-015-2907-0 | ||
| UAK Araştırma Alanları |
Kardiyoloji
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| Özet |
| The etiology of Behçet’s disease (BD) has not been fully elucidated. However, immunological and environmental factors, endothelial dysfunction (ED), and genetic susceptibility have been proposed to play a role. In this study, we aimed to evaluate epicardial fat thickness (EFT) together with serum asymmetric dimethylarginine (ADMA), carotid intima media thickness (CIMT), and neutrophil-to-lymphocyte ratio (NLR) in BD patients with ocular involvement. Thirty-six ocular BD patients (17 active and 19 inactive ocular involvement), and 35 age and sex-matched healthy controls were enrolled to this cross-sectional study. All patients underwent examinations with transthoracic echocardiography and carotid Doppler ultrasound. Serum ADMA levels, CIMT, EFT, and NLR were compared between groups, and their association with disease activity was evaluated. Behçet’s disease patients had higher WBC counts … |
| Anahtar Kelimeler |
| ADMA | Asymmetric dimethylarginine | Behçet’s disease | Carotid intima media thickness | Neutrophil to lymphocyte ratio | Rheumatic diseases |
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| Web of Science | 35 |
| Scopus | 40 |