| Yazarlar |
Halit Acet
|
|
Faruk Ertaş
|
|
Mehmet Ata Akıl
|
|
Ferhat Özyurtlu
|
Prof. Dr. Abdulkadir YILDIZ
Dicle Üniversitesi, Türkiye |
|
Nihat Polat
|
|
Mehmet Zihni Bilik
|
|
Mesut Aydin
|
|
Mustafa Oylumlu
|
|
Hasan Kaya
|
|
Murat Yüksel
|
|
Abdurrahman Akyuz
|
|
Hilal Ayçiçek
|
|
Sait Alan
|
|
Nizamettin Toprak
|
| Özet |
| Objective: The neutrophil/lymphocyte ratio (NLR), the platelet/lymphocyte ratio (PLR), and uric acid (UA) are inflammatory markers in cardiovascular disease. However, there are not enough data on infarct-related artery (IRA) patency in ST-segment elevation myocardial infarction (STEMI). We aimed to investigate the association of NLR, PLR, and UA with IRA patency before percutaneous coronary intervention (PCI) in STEMI. Methods: The study was designed as a retrospective study. Three hundred and twenty-four consecutive patients with STEMI were divided into two groups according to pre-PCI Thrombolysis in Myocardial Infarction flow grade (TIMI). Patients with a TIMI flow grade of into the spontaneous reperfusion (SR) group, while patients with TIMI flow grade of 0, 1 and 2 were placed into the non-SR group. The χ2 and independentsamples t-test, Mann-Whitney U test, multivariate logistic regression analysis, and receiver-operator characteristic (ROC) curve analysis were used for the statistical analysis. Results: PLR, NLR, and UA values in the SR group were lower than in the non-SR group (p<0.004, p<0.001, p<0.001, respectively). In the multivariate analysis, serum UA level and PLR were found to be independent predictors of pre-PCI IRA patency. In the ROC curve analysis, PLR >190, UA>5.75 mg/dL, and NLR>4.2 predicted non-SR. The sensitivity and specificity of the association between low IRA TIMI flow grade and PLR were 88% and 84%, 72% and 66% for UA, and 74% and 44% for NLR, respectively. Conclusion: We determined that PLR and UA are novel predictors of IRA patency before PCI. We suggest that PLR and UA may be used in riskstratifying STEMI. |
| Anahtar Kelimeler |
| platelet-to-lymphocyte ratio,uric acid,neutrophil-to-lymphocyte ratio,coronary angiography,acute myocardial infarction,infarct-related artery patency |
| Makale Türü | Özgün Makale |
| Makale Alt Türü | SSCI, AHCI, SCI, SCI-Exp dergilerinde yayımlanan tam makale |
| Dergi Adı | The Anatolian Journal of Cardiology |
| Dergi ISSN | 2149-2263 |
| Dergi Tarandığı Indeksler | SCI-Expanded |
| Makale Dili | İngilizce |
| Basım Tarihi | 08-2015 |
| Cilt No | 15 |
| Sayı | 8 |
| Sayfalar | 648 / 656 |
| Doi Numarası | 10.5152/akd.2014.5592 |
| Makale Linki | https://www.journalagent.com/anatoljcardiol/pdfs/AnatolJCardiol_15_8_648_656.pdf |
| Atıf Sayıları | |
| WoS | 29 |
| SCOPUS | 11 |
| TRDizin | 5 |
