The association between the neutrophil/lymphocyte ratio and functional capacity in patients with idiopathic dilated cardiomyopathy
 
Yazarlar (6)
Prof. Dr. Abdulkadir YILDIZ Dicle Üniversitesi, Türkiye
Murat Yüksel Dicle Üniversitesi, Türkiye
Prof. Dr. Mustafa Oylumlu Dicle Üniversitesi, Türkiye
Prof. Dr. Nihat Polat Dicle Üniversitesi, Türkiye
Mehmet Ata Akıl Dicle Üniversitesi, Türkiye
Prof. Dr. Halit Acet Dicle Üniversitesi, Türkiye
Makale Türü Açık Erişim Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale)
Dergi Adı Anadolu Kardiyoloji Dergisi
Dergi ISSN 1302-8723
Dergi Tarandığı Indeksler SCI-Expanded
Makale Dili İngilizce Basım Tarihi 01-2015
Kabul Tarihi Yayınlanma Tarihi 22-01-2015
Cilt / Sayı / Sayfa 15 / 1 / 13–17 DOI 10.5152/akd.2014.5131
Makale Linki https://www.journalagent.com/anatoljcardiol/pdfs/AnatolJCardiol_15_1_13_17.pdf
UAK Araştırma Alanları
Kardiyoloji
Özet
Objective: The neutrophil/lymphocyte ratio (NLR) is an inexpensive, readily available and reliable inflammatory marker, which has a predictor value in different cardiovascular disorders. Functional capacity is one of the most important prognostic factors in patients with heart failure, which is usually stated as metabolic equivalents (MET). The goal of the study was to investigate the relationship between the NLR and functional capacity (FC) in patients with idiopathic dilated cardiomyopathy (IDC). Methods: Treadmill test according to modified-Bruce protocol was performed in 37 patients with IDC (mean age 46.7±11.7 years, 81.1% male) to assess their functional capacity. Baseline clinical and echocardiographic variables were obtained. Hematological and biochemical parameters were measured using standard techniques.Results: The patients were divided into low (< 5 MET, n= 18) and high (> 5 MET, n= 19) FC groups according to their functional status in the exercise test. The 2 groups were similar regarding age, gender and the presence of hypertension and diabetes mellitus. There was no significant difference between groups regarding echocardiographic parameters such as left ventricular ejection fraction and diameters. However, the NLR was significantly higher in low FC group compared to high FC group (3.62±2.24 vs. 2.24±0.67, p= 0.002; respectively). There were significant negative correlations between the NLR, MET and left ventricular ejection fraction (r=-0.405, p= 0.013 and r=-0.028, p= 0.028; respectively). Diastolic dysfunction was present in all the patients with low functional capacity. A cut-off point of 2.26 for the NLR had 83 …
Anahtar Kelimeler
Functional capacity | Heart failure | Idiopathic dilated cardiomyopathy | Neutrophil/lymphocyte ratio