img
The Utility of the Platelet–Lymphocyte Ratio for Predicting No Reflow in Patients With ST-Segment Elevation Myocardial Infarction      
Yazarlar
Prof. Dr. Abdulkadir YILDIZ
Dicle Üniversitesi, Türkiye
Murat Yüksel
Mustafa Oylumlu
Nihat Polat
Abdurrahman Akyuz
Halit Acet
Mesut Aydın
Mehmet Sıddık Ulgen
Özet
The aim of the study was to evaluate the utility of the preprocedural platelet-lymphocyte ratio (PLR) for predicting no reflow in patients undergoing primary percutaneous intervention (PCI) for the treatment of ST-segment elevation myocardial infarction. The thrombolysis in myocardial infarction (TIMI) flow grades of 287 patients treated with primary PCI were assessed retrospectively. Patients were divided into 3 tertiles based upon preprocedural PLR. Pre- and postprocedural TIMI flow grades were evaluated. No reflow developed in 6, 14, and 43 patients in the lower, middle, and higher tertiles, respectively (P <.001). After multivariate analysis, PLR remained a significant predictor of no reflow together with neutrophil-lymphocyte ratio (NLR). A cutoff value of 160 for PLR and 5.9 for NLR predicted no reflow with sensitivities and specificities of 75% and 71% and 74% and 70%, respectively. In conclusion, high preprocedural PLR and NLR levels are significant and independent predictors of no reflow in patients undergoing primary PCI.
Anahtar Kelimeler
primary percutaneous coronary intervention,acute ST-segment elevation myocardial infarction,platelet to lymphocyte ratio,no reflow
Makale Türü Özgün Makale
Makale Alt Türü SSCI, AHCI, SCI, SCI-Exp dergilerinde yayımlanan tam makale
Dergi Adı Clinical and Applied Thrombosis/Hemostasis
Dergi ISSN 1076-0296
Dergi Tarandığı Indeksler SCI-Expanded
Makale Dili İngilizce
Basım Tarihi 08-2014
Cilt No 21
Sayı 3
Sayfalar 223 / 228
Doi Numarası 10.1177/1076029613519851
Makale Linki http://journals.sagepub.com/doi/10.1177/1076029613519851