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The Association Between the Neutrophil to Lymphocyte Ratio and the Presence of Ventricular Premature Contractions in Young Adults      
Yazarlar
Prof. Dr. Abdulkadir YILDIZ
Dicle Üniversitesi, Türkiye
Mustafa Oylumlu
Murat Yüksel
Mesut Aydın
Nihat Polat
Halit Acet
Mehmet Ata Akıl
Mehmet Zihni Bilik
Hasan Kaya
Faruk Ertaş
Özet
Inflammation has recently emerged in the pathogenesis of several cardiovascular disorders, including arrhythmias. The neutrophil-lymphocyte ratio (NLR) is a simple marker for the assessment of inflammatory status. Therefore, we aimed to investigate the relationship between the NLR and the ventricular premature contraction (VPC) existence. Patients aged between 18 and 40 years who were referred to the cardiology clinic were enrolled in the study. All patients' complete blood counts and 24-hour Holter recordings were analyzed. The NLR was higher within the VPC group compared to the control group (P <.001). According to the NLR tertiles, VPCs were more common in the higher NLR tertile (P <.001). A cutoff point of 1.80 for the NLR had 71% sensitivity and 60% specificity in predicting VPC in apparently healthy individuals. After multivariate analysis, only the NLR remained significant predictor of presence of VPC. In conclusion, the NLR is independently and significantly associated with VPC existence.
Anahtar Kelimeler
inflammation,neutrophil-to-lymphocyte ratio,ventricular premature contraction
Makale Türü Özgün Makale
Makale Alt Türü SSCI, AHCI, SCI, SCI-Exp dergilerinde yayımlanan tam makale
Dergi Adı Clinical and Applied Thrombosis/Hemostasis
Dergi ISSN 1076-0296
Dergi Tarandığı Indeksler SCI-Expanded
Makale Dili İngilizce
Basım Tarihi 07-2015
Cilt No 21
Sayı 5
Sayfalar 475 / 479
Doi Numarası 10.1177/1076029613509478
Makale Linki http://cat.sagepub.com/cgi/doi/10.1177/1076029613509478