Relation of epicardial fat thickness and brachial flow mediated vasodilation with coronary artery disease
Yazarlar (10)
Hasan Kaya Dicle Üniversitesi, Türkiye
Faruk Ertas Dicle Üniversitesi, Türkiye
Mustafa Oylumlu Dicle Üniversitesi, Türkiye
Mehmet Zihni Bilik Dicle Üniversitesi, Türkiye
Prof. Dr. Abdulkadir YILDIZ Dicle Üniversitesi, Türkiye
Murat Yuksel Dicle Üniversitesi, Türkiye
Nihat Polat Dicle Üniversitesi, Türkiye
Halit Acet Dicle Üniversitesi, Türkiye
Ferhat Isik Dicle Üniversitesi, Türkiye
Mehmet Siddik Ulgen Dicle Üniversitesi, Türkiye
| Makale Türü |
Özgün Makale
(SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale)
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| Dergi Adı | Journal of Cardiology | ||
| Dergi ISSN | 0914-5087 Wos Dergi Scopus Dergi | ||
| Dergi Tarandığı Indeksler | SCI-Expanded | ||
| Makale Dili | İngilizce | Basım Tarihi | 12-2013 |
| Cilt / Sayı / Sayfa | 62 / 6 / 343–347 | DOI | 10.1016/j.jjcc.2013.05.009 |
| Makale Linki | http://linkinghub.elsevier.com/retrieve/pii/S0914508713001743 | ||
| Özet |
| Objective: The purpose of this study is to investigate the presence of a statistical association between epicardial fat thickness (EFT) and coronary artery disease (CAD) and between flow-mediated vasodilation (FMD) and CAD. Methods: We measured the EFT and FMD in 64 subjects with suspected stable angina pectoris. The patients were separated into two groups according to their coronary angiography results: 34 patients with CAD and 30 patients with normal coronary arteries (NCA). Results: EFT was significantly higher in the patients with CAD than the NCA group (6.43. ±. 0.90. mm vs. 5.35. ±. 0.75. mm, p<. 0.001) while FMD was significantly lower in the patients with CAD than those in the NCA group (6.41. ±. 2.51% vs. 8.33. ±. 3.45%, p= 0.015). No significant correlation was found between EFT and FMD. After adjustment for EFT, FMD, age, sex, ejection fraction, glucose, and low-density lipoprotein cholesterol through multivariate logistic regression analysis, EFT (odds ratio: 6.325, 95% confidence interval 2.289-17.476, p<. 0.001) and age (odds ratio: 1.093, 95% confidence interval 1.008-1.185, p= 0.032) remained significant predictors of CAD. A cut-off value of EFT. ≥. 5.8. mm predicted the presence of CAD with 77% sensitivity and 70% specificity. Conclusion: An echocardiographic EFT assessment is independently associated with the presence of CAD. Thus, EFT may be helpful in cardiometabolic risk stratification and therapeutic interventions. © 2013 Japanese College of Cardiology. |
| Anahtar Kelimeler |
| Coronary artery disease | Epicardial fat thickness | Flow-mediated vasodilation |
Science Direct
Relation of epicardial fat thickness and brachial flow mediated vasodilation with coronary artery disease
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| Web of Science | 12 |
| Scopus | 15 |