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New inflammatory predictors for non valvular atrial fibrillation echocardiographic epicardial fat thickness and neutrophil to lymphocyte ratio      
Yazarlar
Acet Halit
Ertas Faruk
Akil Mehmet Ata
Oylumlu Mustafa
Polat Nihat
Yildiz Abdulkadir
Bilik Mehmet Zihni
Yuksel Murat
Kaya Zeynettin
Ulgen Mehmet Sıddık
Özet
The objective of this study was to investigate the relationship of echocardiographic epicardial fat thickness (EFT) and neutrophil to lymphocyte ratio (NLR) with different types of non-valvular atrial fibrillation (AF) in a clinical setting. A total of 197 consecutive patients were enrolled in the study. Seventy-one patients had paroxysmal non-valvular AF, 63 patients had persistent/permanent nonvalvular AF, and 63 patients had sinus rhythm (control group). EFT was measured with echocardiography, while NLR was measured by dividing neutrophil count by lymphocyte count. EFT was significantly higher in patients with paroxysmal non-valvular AF compared with those in the sinus rhythm group (6.6 ± 0.7 vs. 5.0 ± 0.9 mm, p < 0.001). Persistent/permanent non-valvular AF patients had a significantly larger EFT compared with those with paroxysmal AF (8.3 ± 1.1 vs. 6.6 ± 0.7 mm, p < 0.001). EFT had a significant relationship with paroxysmal nonvalvular AF (odds ratio 4.672, 95% CI 2.329-9.371, p < 0.001) and persistent/permanent non-valvular AF (OR 24.276, 95% CI 9.285-63.474, p < 0.001). NLR was significantly higher in those with paroxysmal non-valvular AF compared with those in the sinus rhythm group (2.5 ± 0.6 vs. 1.8 ± 0.4, p < 0.001). Persistent/permanent non-valvular AF patients had a significantly larger NLR when compared with paroxysmal non-valvular AF patients (3.4 ± 0.6, vs. 2.5 ± 0.6, p < 0.001). NLR (>2.1) had a significant relationship with non-valvular AF (OR 11.313, 95% CI 3.025-42.306, b 2.426, p < 0.001). EFT and NLR are highly associated with types of non-valvular AF independent of traditional risk factors. EFT measured by echocardiography and NLR appears to be related to the duration and severity of AF. © Springer Science+Business Media 2013.
Anahtar Kelimeler
Epicardial fat thickness,Echocardiography,Neutrophil to lymphocyte ratio,Non-valvular atrial fibrillation,Left atrial enlargement
Makale Türü Özgün Makale
Makale Alt Türü SSCI, AHCI, SCI, SCI-Exp dergilerinde yayımlanan tam makale
Dergi Adı The International Journal of Cardiovascular Imaging
Dergi ISSN 1569-5794
Dergi Tarandığı Indeksler SCI
Makale Dili İngilizce
Basım Tarihi 01-2014
Cilt No 30
Sayı 1
Sayfalar 81 / 89
Doi Numarası 10.1007/s10554-013-0317-4
Makale Linki http://link.springer.com/10.1007/s10554-013-0317-4