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Epidemiology anticoagulant treatment and risk of thromboembolism in patients with valvular atrial fibrillation Results from Atrial Fibrillation in Turkey Epidemiologic Registry AFTER      
Yazarlar
Hasan Kaya
Faruk Ertas
Zekeriya Kaya
Nihan Kahya Eren
Murat Yuksel
Bayram Koroglu
Nuri Kose
Prof. Dr. Abdulkadir YILDIZ
Kastamonu Üniversitesi
Tolga Cimen
Mehmet Siddik Ulgen
Özet
Background: The aim of this study was to perform a multicenter, prospective investigation regarding the epidemiology, the current effectiveness of therapeutic anticoagulation, and the risk of thromboembolism in patients with valvular atrial fibrillation (AF) based on the records of the Atrial Fibrillation in Turkey: Epidemiologic Registry (AFTER) study. Methods: Patients were selected from a total of 2,242 consecutive admissions that presented with AF diagnosed via electrocardiogram. Those diagnosed with non-valvular AF were excluded from the AFTER study population, which left 497 patients with valvular AF for analysis. Results: The etiology of valvular AF in patients was either attributed to rheumatic mitral valve stenosis (n = 217) or possessing a prosthetic heart valve (n = 280). Out of all the patients with valvular AF, 83.1% were taking warfarin for anticoagulation. Only 36.1% demonstrated a therapeutic international normalized ratio (INR), and among those patients it was found that 19.1% exhibited a labile INR. Multivariate analysis revealed that age was the only independent predictor of thromboembolic events in patients with valvular AF. Conclusions: Many valvular AF patients are not maintained at therapeutic INR levels, which poses a threat to patient health as they age and are at greater risk for thromboembolism. © 2014 Via Medica.
Anahtar Kelimeler
Anticoagulant treatment | Atrial fibrillation | Predictor | Valvular
Makale Türü Özgün Makale
Makale Alt Türü SSCI, AHCI, SCI, SCI-Exp dergilerinde yayımlanan tam makale
Dergi Adı CARDIOLOGY JOURNAL
Dergi ISSN 1897-5593
Dergi Tarandığı Indeksler SCI-Expanded
Makale Dili İngilizce
Basım Tarihi 03-2014
Cilt No 21
Sayı 2
Sayfalar 158 / 162
Doi Numarası 10.5603/CJ.a2013.0085
Makale Linki http://czasopisma.viamedica.pl/cj/article/view/34235