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Association of Neutrophil Lymphocyte Ratio With the Presence and Severity of Rheumatic Mitral Valve Stenosis      
Yazarlar
Nihat Polat
Prof. Dr. Abdulkadir YILDIZ Prof. Dr. Abdulkadir YILDIZ
Kastamonu Üniversitesi
Murat Yuksel
Mehmet Zihni Bilik
Mesut Aydin
Halit Acet
Mehmet Ata Akil
Mustafa Oylumlu
Hasan Kaya
Faruk Ertas
Habib Cil
Özet
The aim of the study is to investigate the association between the severity of rheumatic mitral valvular disease (RMVD) and the neutrophil-lymphocyte ratio (NLR). A total of 227 patients were enrolled in the study and divided into 3 groups. Patients in group 1 had rheumatic mitral stenosis (RMS), those in group 2 had RMVD without stenosis, and those in group 3 served as the control group. Group 1 was further divided into 2 groups, severe mitral stenosis (MS) and mild to moderate MS. The NLR was significantly higher in patients with severe MS when compared to those with mild to moderate MS (P =.002) while lymphocyte count was lower (P =.034). Using a cutoff level of 2.56, the NLR predicted severe RMS with a sensitivity of 75% and specificity of 74%. In conclusion, as an inexpensive, simple, and accessible marker of inflammation, the NLR may be useful in predicting the presence and severity of MS in patients with RMVD.
Anahtar Kelimeler
inflammation | mitral stenosis | neutrophil to lymphocyte ratio | rheumatic valve disease
Makale Türü Özgün Makale
Makale Alt Türü SSCI, AHCI, SCI, SCI-Exp dergilerinde yayımlanan tam makale
Dergi Adı CLINICAL AND APPLIED THROMBOSIS-HEMOSTASIS
Dergi ISSN 1076-0296
Dergi Tarandığı Indeksler SCI-Expanded
Makale Dili İngilizce
Basım Tarihi 11-2014
Cilt No 20
Sayı 8
Sayfalar 793 / 798
Doi Numarası 10.1177/1076029613514131
Makale Linki http://cat.sagepub.com/cgi/doi/10.1177/1076029613514131