Yazarlar |
Nihat Polat
|
Prof. Dr. Abdulkadir YILDIZ
Kastamonu Üniversitesi |
Murat Yuksel
|
Mehmet Zihni Bilik
|
Mesut Aydin
|
Halit Acet
|
Mehmet Ata Akil
|
Mustafa Oylumlu
|
Hasan Kaya
|
Faruk Ertas
|
Habib Cil
|
Özet |
The aim of the study is to investigate the association between the severity of rheumatic mitral valvular disease (RMVD) and the neutrophil-lymphocyte ratio (NLR). A total of 227 patients were enrolled in the study and divided into 3 groups. Patients in group 1 had rheumatic mitral stenosis (RMS), those in group 2 had RMVD without stenosis, and those in group 3 served as the control group. Group 1 was further divided into 2 groups, severe mitral stenosis (MS) and mild to moderate MS. The NLR was significantly higher in patients with severe MS when compared to those with mild to moderate MS (P =.002) while lymphocyte count was lower (P =.034). Using a cutoff level of 2.56, the NLR predicted severe RMS with a sensitivity of 75% and specificity of 74%. In conclusion, as an inexpensive, simple, and accessible marker of inflammation, the NLR may be useful in predicting the presence and severity of MS in patients with RMVD. |
Anahtar Kelimeler |
inflammation | mitral stenosis | neutrophil to lymphocyte ratio | rheumatic valve disease |
Makale Türü | Özgün Makale |
Makale Alt Türü | SSCI, AHCI, SCI, SCI-Exp dergilerinde yayımlanan tam makale |
Dergi Adı | CLINICAL AND APPLIED THROMBOSIS-HEMOSTASIS |
Dergi ISSN | 1076-0296 |
Dergi Tarandığı Indeksler | SCI-Expanded |
Makale Dili | İngilizce |
Basım Tarihi | 11-2014 |
Cilt No | 20 |
Sayı | 8 |
Sayfalar | 793 / 798 |
Doi Numarası | 10.1177/1076029613514131 |
Makale Linki | http://cat.sagepub.com/cgi/doi/10.1177/1076029613514131 |