High Neutrophil/Lymphocyte Ratios in Symptomatic Pediatric COVID-19 Patients
Yazarlar (5)
Doç. Dr. Eren YILDIZ Kastamonu Üniversitesi, Türkiye
Doç. Dr. Emrah ÇIĞRI Kastamonu Üniversitesi, Türkiye
Zübeyde Dinçer
Kastamonu State Hospital, Türkiye
Kastamonu State Hospital, Türkiye
Mehmet Ali Narsat
Kastamonu State Hospital, Türkiye
Kastamonu State Hospital, Türkiye
Büşra Çalışır Kastamonu State Hospital, Türkiye
| Makale Türü |
Özgün Makale
(SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale)
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| Dergi Adı | Journal of the College of Physicians and Surgeons Pakistan | ||
| Dergi ISSN | 1022-386X Wos Dergi Scopus Dergi | ||
| Dergi Tarandığı Indeksler | SCI-Expanded | ||
| Makale Dili | İngilizce | Basım Tarihi | 07-2021 |
| Cilt / Sayı / Sayfa | 31 / 7 / – | DOI | 10.29271/jcpsp.2021.Supp2.S93 |
| Makale Linki | http://dx.doi.org/10.29271/jcpsp.2021.supp2.s93 | ||
| UAK Araştırma Alanları |
Çocuk Sağlığı ve Hastalıkları (Çocuk Sağlığı ve Hastalıkları)
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| Özet |
| Objective: To investigate the symptoms and laboratory results of children hospitalised with the diagnosis of COVID-19, aiming to reveal the characteristics of symptomatic cases. Study Design: A descriptive cross-sectional study. Place and Duration of Study: Department of Pediatrics, Kastamonu Training and Research Hospital, Kastamonu, Turkey from March to December 2020. Methodology: Seventy-nine children, hospitalised with the diagnosis of COVID-19, were included in the study and were divided into two groups as symptomatic and asymptomatic. The demographic data, laboratory results and clinics of the patients of the two groups were compared. Results: The mean age of participants was 10.43 5.91 (0-17) years, and 57% (n=45) of them were girls. Five patients in the symptomatic group had comorbidities (2 allergic asthma, cerebral palsy, type-1 diabetes mellitus and anorexia nervosa). The most common symptom was fever (36.7%, n=29). It was noteworthy that everyone with an NLR 3.13 (high-NLR) was symptomatic. Significantly more patients in the high-NLR group were symptomatic compared with the low-NLR group (p=0.005). On the other hand, symptomatic children had significantly higher levels of C-reactive protein (2.8 (IQR: 1.2-10.0) mg/L vs. 1.4 (IQR: 0.4-2.0) mg/L, p=0.011); and procalcitonin (0.05 (IQR: 0.02-0.10) ng/mL vs. 0.01 (IQR: 0.00-0.03) ng/mL, p0.001) than those without symptoms. One of the children with cerebral palsy died from pneumonia during the study. Conclusion: C-reactive protein, procalcitonin and NLR levels were found to be significantly higher in symptomatic children. NLR can be suggested as a potential marker associated with disease severity in COVID-19 patients, which needs to be supported by other studies. |
| Anahtar Kelimeler |
| C-reactive protein | Children | COVID-19 | Neutrophil / lymphocyte ratio | Procalcitonin. |
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| Scopus | 8 |