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High Neutrophil/Lymphocyte Ratios in Symptomatic Pediatric COVID-19 Patients    
Yazarlar
Doç. Dr. Eren YILDIZ
Türkiye
Doç. Dr. Emrah ÇIĞRI
Kastamonu Üniversitesi, Türkiye
Zübeyde Dinçer
Türkiye
Mehmet Ali Narsat
Türkiye
Büşra Çalışır
Özet
Objective: To investigate the symptoms and laboratory results of children hospitalised with the diagnosis of COVID-19, aiming to reveal the characteristics of symptomatic cases. Study Design: A descriptive cross-sectional study. Place and Duration of Study: Department of Pediatrics, Kastamonu Training and Research Hospital, Kastamonu, Turkey from March to December 2020. Methodology: Seventy-nine children, hospitalised with the diagnosis of COVID-19, were included in the study and were divided into two groups as symptomatic and asymptomatic. The demographic data, laboratory results and clinics of the patients of the two groups were compared. Results: The mean age of participants was 10.43 5.91 (0-17) years, and 57% (n=45) of them were girls. Five patients in the symptomatic group had comorbidities (2 allergic asthma, cerebral palsy, type-1 diabetes mellitus and anorexia nervosa). The most common symptom was fever (36.7%, n=29). It was noteworthy that everyone with an NLR 3.13 (high-NLR) was symptomatic. Significantly more patients in the high-NLR group were symptomatic compared with the low-NLR group (p=0.005). On the other hand, symptomatic children had significantly higher levels of C-reactive protein (2.8 (IQR: 1.2-10.0) mg/L vs. 1.4 (IQR: 0.4-2.0) mg/L, p=0.011); and procalcitonin (0.05 (IQR: 0.02-0.10) ng/mL vs. 0.01 (IQR: 0.00-0.03) ng/mL, p0.001) than those without symptoms. One of the children with cerebral palsy died from pneumonia during the study. Conclusion: C-reactive protein, procalcitonin and NLR levels were found to be significantly higher in symptomatic children. NLR can be suggested as a potential marker associated with disease severity in COVID-19 patients, which needs to be supported by other studies.
Anahtar Kelimeler
C-reactive protein | Children | COVID-19 | Neutrophil / lymphocyte ratio | Procalcitonin.
Makale Türü Özgün Makale
Makale Alt Türü SSCI, AHCI, SCI, SCI-Exp dergilerinde yayımlanan tam makale
Dergi Adı Journal of the College of Physicians and Surgeons Pakistan
Dergi ISSN 1022-386X
Dergi Tarandığı Indeksler SCI-Expanded
Makale Dili İngilizce
Basım Tarihi 07-2021
Cilt No 31
Sayı 7
Sayfalar 93 / 98
Doi Numarası 10.29271/jcpsp.2021.Supp2.S93
Makale Linki http://dx.doi.org/10.29271/jcpsp.2021.supp2.s93
BM Sürdürülebilir Kalkınma Amaçları
Atıf Sayıları
SCOPUS 7
High Neutrophil/Lymphocyte Ratios in Symptomatic Pediatric COVID-19 Patients

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