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Study of bacteria isolated from COVID-19 and non-COVID-19 intensive care units and determination of their antibiotic susceptibility profiles   
Yazarlar
Çetin Kılınç
Türkiye
Nilay Çöplü
Türkiye
Melike Yaşar Doğan
Büşra Çalışır
Dr. Öğr. Üyesi Enis Fuat TÜFEKCİ
Kastamonu Üniversitesi, Türkiye
Muhammet Gülhan
Türkiye
Doç. Dr. Ayşe YILMAZ
Kastamonu Üniversitesi, Türkiye
Doç. Dr. Veysel Garani SOYLU
Kastamonu Üniversitesi, Türkiye
Özet
Nosocomial infections occur 48-72 hours after hospitalization, especially caused by bacteria, and pose a high risk for patients in intensive care units (ICUs), including COVID-ICUs. This study aimed to reveal bacteria distribution and antibiotic susceptibility profiles isolated from various clinical samples of non-COVID-ICU and COVID-ICU patients. We included in this study bacterial strains isolated from ICUs patients in Kastamonu Training and Research Hospital between March 2020 and October 2020. We identified the strains using the Vitek 2 compact automated system (BioMerieux, France) and standard microbiological methods. Using the Vitek 2 automated system, we analyzed antibiotic susceptibility tests and interpreted the results based on the European Committee for Antimicrobial Susceptibility Tests (EUCAST) guideline. There were 302 patients in the non-COVID-ICUs and 440 patients in the COVID-ICUs. We isolated a total of 470 strains, 370 from non-COVID-ICUs and 100 from COVID-ICUs. Acinetobacter spp. was the most frequently isolated strains for both ICUs. Acinetobacter spp. isolated from non-COVID-ICUs had higher resistance rates to meropenem (p= 0.043), ceftazidime (p= 0.014), and levofloxacin (p<0.001) antibiotics than strains from COVID-ICUs. Antibiotic susceptibility profiles of other strains were similar for both ICUs. As a result, the incidence of nosocomial infections in COVID-ICU patients was lower than in non-COVID-ICU patients. Health personnel working in COVID-ICUs may have played an important role in this, as they were more careful about using personal protective equipment and complying with hygiene rules. However, antibiotic resistance continues to be a serious problem in ICUs, including COVID-ICUs.
Anahtar Kelimeler
Acinetobacter | antibiotic resistance | COVID-intensive care unit | nosocomial infections
Makale Türü Özgün Makale
Makale Alt Türü SCOPUS dergilerinde yayımlanan tam makale
Dergi Adı Journal of Experimental and Clinical Medicine
Dergi ISSN 1309-4483
Dergi Tarandığı Indeksler Scopus
Makale Dili İngilizce
Basım Tarihi 10-2022
Cilt No 39
Sayı 4
Sayfalar 1027 / 1031
Doi Numarası 10.52142/omujecm.39.4.20
Makale Linki https://dergipark.org.tr/en/pub/omujecm/issue/73188/1099585