Effects of astaxanthin on biochemical and histopathological parameters related to oxidative stress on testes of rats on high fructose regime
 
Yazarlar (8)
E. Dokumacioglu
Artvin Coruh University, Türkiye
H. Iskender
Artvin Coruh University, Türkiye
G. Yenice
Atatürk Üniversitesi, Türkiye
K. A.T. Kapakin
Atatürk Üniversitesi, Türkiye
Doç. Dr. Çiğdem SEVİM Atatürk Üniversitesi, Türkiye
A. Hayirli
Atatürk Üniversitesi, Türkiye
S. Saral
Recep Tayyip Erdogan University, Türkiye
S. Comakli
Atatürk Üniversitesi, Türkiye
Makale Türü Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale)
Dergi Adı Andrologia (Q2)
Dergi ISSN 0303-4569 Dergi Bilgileri (2018)
Dergi Tarandığı Indeksler SCI-Expanded
Makale Dili İngilizce Basım Tarihi 09-2018
Kabul Tarihi Yayınlanma Tarihi 09-05-2018
Cilt / Sayı / Sayfa 50 / 7 / 1–10 DOI 10.1111/and.13042
Makale Linki http://doi.wiley.com/10.1111/and.13042
UAK Araştırma Alanları
Tıbbi Farmakoloji
Özet
Astaxanthin (ASX) is a xanthophyll family of hydroxycarotenoids which contains several double bonds. It is produced by Haemococcus pluvialis, a microalgae and possesses antioxidant and anti‐inflammatory properties. The aim of this study was to test whether ASX could protect against oxidative damage in the testicular tissues of rats receiving high fructose. The rats (n = 24) were randomly divided into two main groups: control and fructose (30%, via drinking water) and then each main group either not supplemented or supplemented with ASX (1 mg kg−1 day−1, within 0.2 ml olive oil) via oral gavage. Data were subjected to two‐way ANOVA. High fructose consumption tended to increase testis weight and serum testosterone concentration and decreased testicular tissue glutathione‐S‐transferase (GST) and superoxide dismutase (SOD) levels, but did not affect testicular tissue malondialdehyde (MDA …
Anahtar Kelimeler
astaxanthin | fructose | oxidative stress | testes