Cadmium sulfide-induced toxicity in the cortex and cerebellum: In vitro and in vivo studies
Yazarlar (12)
Atefeh Varmazyari
Atatürk Üniversitesi, Türkiye
Doç. Dr. Ali Taghizadehghalehjoughi Atatürk Üniversitesi, Türkiye
Doç. Dr. Çiğdem SEVİM Atatürk Üniversitesi, Türkiye
Prof. Dr. Ozlem Baris Atatürk Üniversitesi, Türkiye
Dr. Öğr. Üyesi Gizem Eser Iğdır Üniversitesi, Türkiye
Serkan Yildirim Ataturk University, Faculty of Medicine, Türkiye
Prof. Dr. Ahmet Hacimuftuoglu Ataturk University, Faculty of Medicine, Türkiye
Aleksandra Buha
University of Belgrade, Sırbistan
David R. Wallace
Osu College of Osteopathic Medicine, Amerika Birleşik Devletleri
Aristidis Tsatsakis
University of Crete, Yunanistan
Michael Aschner
Albert Einstein College of Medicine, Amerika Birleşik Devletleri
Yaroslav Mezhuev
Mendeleev University of Chemical Technology of Russia, Rusya Federasyonu
Makale Türü Açık Erişim Özgün Makale (ESCI dergilerinde yayınlanan tam makale)
Dergi Adı Toxicology Reports
Dergi ISSN 2214-7500 Dergi Bilgileri (2020)
Dergi Tarandığı Indeksler Scopus
Makale Dili İngilizce Basım Tarihi 01-2020
Kabul Tarihi Yayınlanma Tarihi 01-01-2020
Cilt / Sayı / Sayfa 7 / 1 / 637–648 DOI 10.1016/j.toxrep.2020.04.011
Makale Linki https://linkinghub.elsevier.com/retrieve/pii/S2214750019304202
UAK Araştırma Alanları
Tıbbi Farmakoloji
Özet
Living organisms have an innate ability to regulate the synthesis of inorganic materials, such as bones and teeth in humans. Cadmium sulfide (CdS) can be utilized as a quantum dot that functions as a unique light-emitting semiconductor nanocrystal. The increased use in CdS has led to an increased inhalation and ingestion rate of CdS by humans which requires a broader appreciation for the acute and chronic toxicity of CdS. We investigated the toxic effects of CdS on cerebellar cell cultures and rat brain. We employed a ‘green synthesis’ biosynthesis process to obtain biocompatible material that can be used in living organisms, such as Viridibacillus arenosi K64. Nanocrystal formation was initiated by adding CdCl2 (1 mM) to the cell cultures. Our in vitro results established that increased concentrations of CdS (0.1 μg/mL) lead to decreased cell viability as assessed using 3-[4,5-dimethylthiazole-2-yl]-2,5 …
Anahtar Kelimeler
CdS | Cerebellum neuron | Green synthesis | Neurotoxicity | Quantum dots
Science Direct
BM Sürdürülebilir Kalkınma Amaçları
Atıf Sayıları
Web of Science 48
Scopus 57
Google Scholar 66
Google Scholar 7
Cadmium sulfide-induced toxicity in the cortex and cerebellum: In vitro and in vivo studies

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