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The sesquiterpenoid valerenic acid protects neuronal cells from the detrimental effects of the fungicide benomyl on apoptosis and DNA oxidation    
Yazarlar
Mehtap Kara
İstanbul Üniversitesi, Türkiye
Ezgi Öztaş
Türkiye
Tuğçe Boran
Türkiye
Dr. Öğr. Üyesi Çiğdem SEVİM
Türkiye
Seda Eren Keskin
Türkiye
Arıstıdıs S Veskoukıs
Sergeı V Kuzmın
Arıstıdes M Tsatsakıs
Özet
Valerenic acid (VA), a sesquiterpenoid of the plant , has attracted attention of the research community due to its potential positive role against neurodegenerative diseases induced by chemicals. However, the relevant evidence in the literature is scarce. Therefore, this study aimed to examine the putative protective role of VA on the toxic effects of the fungicide benomyl on SH-SY5Y neural cells.
Anahtar Kelimeler
Valerenic acid,benomyl,DNA damage,oxidative stress,apoptosis,redox-related mechanism
Makale Türü Özgün Makale
Makale Alt Türü SSCI, AHCI, SCI, SCI-Exp dergilerinde yayımlanan tam makale
Dergi Adı HUMAN & EXPERIMENTAL TOXICOLOGY
Dergi ISSN 0960-3271
Dergi Tarandığı Indeksler SCI-Expanded
Dergi Grubu Q3
Makale Dili İngilizce
Basım Tarihi 05-2022
Cilt No 41
Sayfalar 1 / 10
Doi Numarası 10.1177/09603271221101038
Makale Linki http://dx.doi.org/10.1177/09603271221101038