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The role of alveolo-arterial oxygen gradient and pneumonia severity index in predicting mortality in patients with COVID-19 pneumonia   
Yazarlar
Hale Kefeli Çelik
Türkiye
Prof. Dr. Zahide DOĞANAY Prof. Dr. Zahide DOĞANAY
Kastamonu Üniversitesi, Türkiye
Tuğçehan Sezer Akman
Özet
Purpose of the study is to determine the success rates of alveolo-arterial oxygen gradient (AaDO2) and the pneumonia severity index (PSI) in predicting mortality for the patients diagnosed with COVID-19 pneumonia. This retrospective study included patients who were treated with the diagnosis of COVID-19 pneumonia in the ICUs. Demographic characteristics, arterial blood gas values, radiological images and laboratory data of the patients were used through the hospital database and patient files. Group I patients consist of alive and Group II patients consist of deceased persons. 150 of 263 patients included in this study are in Group I and 113 are in Group II. RT-PCR test was positive in 20.9% of the patients. The most common symptom was dyspnea with 76.5% and the most common additional disease was hypertension with 58.1%.65% of patients had radiological involvement in both lungs, and the most common finding was the ground-glass opacity at 71.5%. In predicting mortality, PSI value was 135 in group I and 174 in group II (p<0.001);AaDO2 value was 154.88 mmHg in group I, 177.13 mmHg in group II (p<0.001), and this rate was different between the groups. Sensitivity is found at 84.1% and specificity at 67.3% for PSI, whereas sensitivity is found at 49.6% and specificity at 82.7% for the AaDO2 variable. It is important to estimate the mortality risk earlier for the patients with COVID-19 pneumonia who are also followed up in intensive care units. PSI is beneficial in detecting mortality risk whereas AaDO2 is valuable in determining the surviving patients.
Anahtar Kelimeler
alveolo-arterial oxygen gradient | COVID-19 | mortality | pneumonia severity index
Makale Türü Özgün Makale
Makale Alt Türü SCOPUS dergilerinde yayımlanan tam makale
Dergi Adı Journal of Experimental and Clinical Medicine
Dergi ISSN 1309-5129
Dergi Tarandığı Indeksler SCOPUS
Makale Dili İngilizce
Basım Tarihi 12-2022
Cilt No 39
Sayı 4
Sayfalar 1208 / 1216
Doi Numarası 10.52142/omujecm.39.4.48
Makale Linki https://dergipark.org.tr/en/download/article-file/2558214