| Yazarlar |
Nur Baykara
|
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Halis Akalın
|
|
Mustafa Kemal Arslantaş
Türkiye |
|
Volkan Hancı
Türkiye |
|
Çiğdem Çağlayan
Türkiye |
|
Ferda Kahveci
|
|
Kubilay Demirağ
Türkiye |
|
Canan Baydemir
Türkiye |
|
Mustafa Necmettin Ünal
Türkiye |
|
Pınar Özdemir
|
|
Hülya Ulusoy
Türkiye |
|
Dilek Memiş
Türkiye |
|
Cavidan Arar
|
|
Elif Yılmaz
|
|
Melek Çelik
|
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İsmail Cinel
|
|
Sibel Temür
Türkiye |
|
Mehmet Akif Yaşar
Türkiye |
|
Hamdiye Tutan Çulha
|
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Canan Balcı
Türkiye |
|
Sultan San
|
|
Asena Salbes
|
|
Elçin Özkan
|
|
Onur Palabıyık
Türkiye |
|
Jale Çelik
|
|
Alper Yosunkaya
Türkiye |
|
Faruk Çiçekci
Türkiye |
|
Işıl Özkoçak
|
|
İsmail Katı
Türkiye |
|
Hülya Başar
Türkiye |
|
Sema Turan
|
|
Süheyla Ünver
Türkiye |
|
Ünase Büyükkoçak
Türkiye |
|
Aynur Akın
|
|
Sinan Gürsoy
Türkiye |
|
Demet Tok
|
|
Simay Serin
|
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Seda Dursun Kıter
|
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Hakan Doğan
Türkiye |
|
Abdülkadir Oruç
|
|
Onur Balaban
Türkiye |
|
Dilara Tüfek
Türkiye |
|
İbrahim Kurt
Türkiye |
|
Murat Bilgi
Türkiye |
|
Verda Tuna
|
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Ayşegül Özkök
|
|
Ahmet Şen
Türkiye |
|
Nilay Taş
Türkiye |
|
Hilal Ayoğlu
Türkiye |
|
Berna Kaya Uğur
Türkiye |
|
Sedat Kaya
|
|
Mustafa Kahraman
Türkiye |
Prof. Dr. Zahide DOĞANAY
Türkiye |
|
Gökalp Soykam
|
|
Işıl Köse
|
|
Birgül Yelken
Türkiye |
|
Osman Ekinci
Türkiye |
|
Gönül Ölmez Kavak
Türkiye |
|
Uğur Göktaş
|
|
Türkan Toğal
Türkiye |
|
Nazim Doğan
Türkiye |
|
Murat Gündüz
|
|
Selim Turhanoğlu
Türkiye |
|
Atilla Ramazanoğlu
Türkiye |
|
Füsun Eroğlu
Türkiye |
|
Şaban Yalçın
Türkiye |
|
Hatice Yağmurdur
Türkiye |
|
Atilla Tutak
Türkiye |
|
Ali Aydın Altunkan
Türkiye |
|
Ufuk Kuyrukluyıldız
Türkiye |
|
Gülsüm Oya Hergünsel
Türkiye |
|
Kerem Erkalp
Türkiye |
|
Necati Gökmen
|
|
Murat Aksun
Türkiye |
|
Erkan Sayan
|
|
Onur Özlü
Türkiye |
|
Yavuz Demiraran
Türkiye |
|
Evren Şentürk
Türkiye |
|
Işın Gençay
Türkiye |
|
Hafize Öksüz
Türkiye |
|
Nihan Yapıcı
Türkiye |
|
Aras Pirat
Türkiye |
|
Tuğhan Utku
Türkiye |
|
Ender Gedik
Türkiye |
|
Orhan Behret
|
|
Kadir İdin
İstanbul Medipol Üniversitesi, Türkiye |
|
Hayrettin Daşkaya
Bezm-İ Âlem Vakıf Üniversitesi, Türkiye |
|
Filiz Banu Ethemoğlu
Türkiye |
|
Ali Alagöz
Türkiye |
|
Seval İzdeş
Türkiye |
|
Mustafa Kemal Bayar
Türkiye |
|
Nermin Kelebek Girgin
Türkiye |
|
Lale Karabıyık
Türkiye |
|
Uğur Koca
Türkiye |
|
Nurcan Çubukçu
|
|
Fatma Ülger
Türkiye |
|
Şeyda Efsun Özgünay
Türkiye |
|
Perihan Ergin Özcan
|
|
Başar Erdivanlı
Türkiye |
|
Şenay Göksu Tomruk
Türkiye |
|
Abbas Köse
|
|
Rafi Doğan
Türkiye |
|
Güldem Turan
Türkiye |
|
Osman Arpaz
|
|
Aliye Esmaoğlu
|
|
Musa Salmanoğlu
Türkiye |
|
Özgür Canoler
|
|
Nedim Çekmen
Türkiye |
|
Canan Kandaz
|
|
Gülşen Bulut Kaya
|
|
Melis Türker
Türkiye |
|
İlknur Şeker
|
|
Aysu Hayriye Tezcan
|
|
Halil İbrahim Uzunlar
|
|
Mehmet Akif Yazar
Türkiye |
|
Reyhan Arslantaş
Türkiye |
|
Nalan Adıgüzel
Türkiye |
|
Murat Aksun
|
|
Okay Öztürk
|
|
Zakir Arslan
Türkiye |
|
Özgür Özmen
Türkiye |
|
Günseli Orhun
Türkiye |
|
Evren Büyükfırat
Türkiye |
|
Oya Çimen Budur
|
|
Mehmet Erdem Akçay
Türkiye |
|
Asu Özgültekin
Türkiye |
|
Ertuğrul Kılıç
Türkiye |
|
Makbule Elif Yılmaz
Türkiye |
|
Ömür İlban
Türkiye |
|
Feyza Kargın
Türkiye |
|
Murat Sayın
|
|
Feyza Kargın
|
|
Resul Altuntaş
Türkiye |
|
Hakan Doğan
|
|
Osman Ekinci
|
|
Berna Çalışkan
|
|
Ayşen Erdoğan
|
|
Volkan Alparslan
|
|
Murat Tekin
|
| Özet |
| Background: The prevalence and mortality of sepsis are largely unknown in Turkey, a country with high antibiotic resistance. A national, multicenter, point-prevalence study was conducted to determine the prevalence, causative microorganisms, and outcome of sepsis in intensive care units (ICUs) in Turkey. Methods: A total of 132 ICUs from 94 hospitals participated. All patients (aged > 18 years) present at the participating ICUs or admitted for any duration within a 24-h period (08:00 on January 27, 2016 to 08:00 on January 28, 2016) were included. The presence of systemic inflammatory response syndrome (SIRS), severe sepsis, and septic shock were assessed and documented based on the consensus criteria of the American College of Chest Physicians and Society of Critical Care Medicine (SEPSIS-I) in infected patients. Patients with septic shock were also assessed using the SEPSIS-III definitions. Data regarding demographics, illness severity, comorbidities, microbiology, therapies, length of stay, and outcomes (dead/alive during 30 days) were recorded. Results: Of the 1499 patients included in the analysis, 237 (15.8%) had infection without SIRS, 163 (10.8%) had infection with SIRS, 260 (17.3%) had severe sepsis without shock, and 203 (13.5%) had septic shock. The mortality rates were higher in patients with severe sepsis (55.7%) and septic shock (70.4%) than those with infection alone (24.8%) and infection + SIRS (31.2%) (p < 0.001). According to SEPSIS-III, 104 (6.9%) patients had septic shock (mortality rate, 75.9%). The respiratory system (71.6%) was the most common site of infection, and Acinetobacter spp. (33.7%) were the most common isolated pathogen. Approximately, 74.9%, 39.1%, and 26.5% of Acinetobacter, Klebsiella, and Pseudomonas spp. isolates, respectively, were carbapenem-resistant, which was not associated with a higher mortality risk. Age, acute physiology and chronic health evaluation II score at ICU admission, sequential organ failure assessment score on study day, solid organ malignancy, presence of severe sepsis or shock, Candida spp. infection, renal replacement treatment, and a nurse-to-patient ratio of 1:4 (compared with a nurse-to-patient ratio of 1:2) were independent predictors of mortality in infected patients. Conclusions: A high prevalence of sepsis and an unacceptably high mortality rate were observed in Turkish ICUs. Although the prevalence of carbapenem resistance was high in Turkish ICUs, it was not associated with a higher risk for mortality. |
| Anahtar Kelimeler |
| Carbapenem resistance | Intensive care | Point prevalence | Sepsis | Turkey |
| Makale Türü | Özgün Makale |
| Makale Alt Türü | SSCI, AHCI, SCI, SCI-Exp dergilerinde yayımlanan tam makale |
| Dergi Adı | Critical Care |
| Dergi ISSN | 1364-8535 |
| Dergi Tarandığı Indeksler | SCI-Expanded |
| Makale Dili | Türkçe |
| Basım Tarihi | 01-2018 |
| Cilt No | 22 |
| Sayfalar | 1 / 14 |
| Doi Numarası | 10.1186/s13054-018-2013-1 |
| Makale Linki | http://dx.doi.org/10.1186/s13054-018-2013-1 |
| Atıf Sayıları | |
| SCOPUS | 81 |
