| Yazarlar |
Göktuğ Savaş
Türkiye |
|
Ömer Şahin
Türkiye |
Dr. Öğr. Üyesi Mustafa YAŞAN
Kastamonu Üniversitesi, Türkiye |
|
Uğur Karabıyık
Türkiye |
|
Nihat Kalay
Türkiye |
|
Ali Doğan
Erciyes Üniversitesi, Türkiye |
|
Ferhan Elmalı
Türkiye |
|
Abdurrahman Oğuzhan
Türkiye |
| Özet |
| Background/aim: Diagnosing and managing functional mitral regurgitation (MR) is often challenging and requires an integrated approach including a comprehensive echocardiographic examination. However, the effects of volume overload on the echocardiographic assessment of MR severity are uncertain. The purpose of this study was to weigh the effects of volume overload in the echocardiographic assessment of MR severity among patients with heart failure (HF). Materials and methods: Twenty-nine patients with decompensated HF, who had moderate or severe MR, were included in the present study. The volume status and the N-terminal pro-B-type natriuretic peptide (proBNP) levels were recorded and the echocardiographic parameters were assessed. After the conventional treatment for HF, the proBNP levels and the echocardiographic parameters were assessed again. Results: The mean age of the patients was 72 ± 9 years and the average hospitalization time was 10.9 ± 5.9 days. Between the beginning and the end of the treatment, there were significant reductions in the effective regurgitant orifice area (EROA) (0.36 ± 0.09 cm2 to 0.29 ± 0.09 cm2, P < 0.001), vena contracta (VC) (P < 0.001), the regurgitant volume (RV) (P < 0.001), and systolic pulmonary artery pressure (sPAP) (P < 0.001). Conclusion: This is the first study to investigate the relationship of changes in severity of MR with volume-load by monitoring the proBNP levels among patients with HF. The present results demonstrated that volume reduction, as evidenced by a decline in the proBNP levels, was accompanied by a marked reduction in the EROA, VC, and the RV among patients with left ventricular dysfunction. |
| Anahtar Kelimeler |
| Functional mitral regurgitation,BNP,volume overload,heart failure,echocardiography |
| Makale Türü | Özgün Makale |
| Makale Alt Türü | SSCI, AHCI, SCI, SCI-Exp dergilerinde yayımlanan tam makale |
| Dergi Adı | TURKISH JOURNAL OF MEDICAL SCIENCES |
| Dergi ISSN | 1303-6165 |
| Dergi Tarandığı Indeksler | SCI-Expanded |
| Dergi Grubu | Q4 |
| Makale Dili | Türkçe |
| Basım Tarihi | 10-2020 |
| Cilt No | 50 |
| Sayı | 6 |
| Sayfalar | 1552 / |
| Doi Numarası | 10.3906/sag-2001-220 |
| Makale Linki | http://dx.doi.org/10.3906/sag-2001-220 |
| Atıf Sayıları | |
| WoS | 2 |
| SCOPUS | 2 |
