Serum levels of nesfatin-1 and irisin in obese children
 
Yazarlar (5)
Prof. Dr. Eda Dokumacıoğlu Artvin Çoruh Üniversitesi, Türkiye
Prof. Dr. Hatice İskender Artvin Çoruh Üniversitesi, Türkiye
Doç. Dr. Arzu Şahin Uşak Üniversitesi, Türkiye
Emine Yurdakul Ertürk Ordu Üniversitesi, Türkiye
Prof. Dr. Özgür KAYNAR Atatürk Üniversitesi, Türkiye
Makale Türü Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale)
Dergi Adı European Cytokine Network
Dergi ISSN 1148-5493
Dergi Tarandığı Indeksler SCI-Expanded
Makale Dili İngilizce Basım Tarihi 03-2020
Cilt / Sayı / Sayfa 31 / 1 / 39–43 DOI 10.1684/ecn.2020.0444
Özet
Background: Along with the developing technology in the modern age, physical activity had decreased considerably in children and adolescents alike with a concomittant and rapid increase in the prevalence of childhood obsesity. The purpose of the present study is to measure the levels of serum nesfatin-1 and irisin in obese children. Methods: The present study was carried out with a total of 62 children, including 32 obese children diagnosed between June 2017 and October 2017 and 30 healthy children. Serum nesfatin-1, irisin, SOD,MDA, fasting blood glucose, total cholesterol (TC), triglyceride (TG), HDL-C, LDL-C, aspartate amino transferase (AST), alanine amino transferase (ALT)), blood urea nitrogen (BUN), C-reactive protein (CRP), calcium (Ca), sodium (Na), potassium (P), chromium (Cr), ferritin, and vitamin B12 data were collected for each patient. Results: In our study, mean nesfatin-1 and SOD values of the obesity group were lower than those of the control group (p <0.05, p <0.001), whereas irisin and MDA values were higher than those of the control group (p <0.001). Conclusion: Childhood obesity is still a significant global problem, despite increased social awareness and numerous preventive healthcare interventions. We believe that all the prospective studies to be carried out to evaluate the relationship between obesity-irisin-nesfatin-1 triad, will make positive contributions to treatment of obesity.
Anahtar Kelimeler
Irisin | nesfatin-1 | obesity | oxidative stress
BM Sürdürülebilir Kalkınma Amaçları
Atıf Sayıları
Web of Science 18
Scopus 19
Serum levels of nesfatin-1 and irisin in obese children

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