| Yazarlar |
Eda Dokumacıoğlu
Artvin Çoruh Üniversitesi, Türkiye |
|
Hatice İskender
Artvin Çoruh Üniversitesi, Türkiye |
|
Arzu Şahin
Uşak Üniversitesi, Türkiye |
|
Emine Yurdakul Ertürk
Ordu Üniversitesi, Türkiye |
Prof. Dr. Özgür KAYNAR
Atatürk Üniversitesi, Türkiye |
| Özet |
| Background: Along with the developing technology in the modern age, physical activity had decreased considerably in children and adolescents alike with a concomittant and rapid increase in the prevalence of childhood obsesity. The purpose of the present study is to measure the levels of serum nesfatin-1 and irisin in obese children. Methods: The present study was carried out with a total of 62 children, including 32 obese children diagnosed between June 2017 and October 2017 and 30 healthy children. Serum nesfatin-1, irisin, SOD,MDA, fasting blood glucose, total cholesterol (TC), triglyceride (TG), HDL-C, LDL-C, aspartate amino transferase (AST), alanine amino transferase (ALT)), blood urea nitrogen (BUN), C-reactive protein (CRP), calcium (Ca), sodium (Na), potassium (P), chromium (Cr), ferritin, and vitamin B12 data were collected for each patient. Results: In our study, mean nesfatin-1 and SOD values of the obesity group were lower than those of the control group (p <0.05, p <0.001), whereas irisin and MDA values were higher than those of the control group (p <0.001). Conclusion: Childhood obesity is still a significant global problem, despite increased social awareness and numerous preventive healthcare interventions. We believe that all the prospective studies to be carried out to evaluate the relationship between obesity-irisin-nesfatin-1 triad, will make positive contributions to treatment of obesity. |
| Anahtar Kelimeler |
| Irisin | nesfatin-1 | obesity | oxidative stress |
| Makale Türü | Özgün Makale |
| Makale Alt Türü | SSCI, AHCI, SCI, SCI-Exp dergilerinde yayımlanan tam makale |
| Dergi Adı | EUROPEAN CYTOKINE NETWORK |
| Dergi ISSN | - |
| Dergi Tarandığı Indeksler | SCI-Expanded |
| Makale Dili | İngilizce |
| Basım Tarihi | 03-2020 |
| Cilt No | 31 |
| Sayı | 1 |
| Sayfalar | 39 / 43 |
| Doi Numarası | 10.1684/ecn.2020.0444 |
| Atıf Sayıları | |
| WoS | 14 |
| SCOPUS | 15 |
