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Reliability of the Lactate Scout point of care analyzer for the determination of blood L lactate concentration in sheep     
Yazarlar
Prof. Dr. Özgür KAYNAR Prof. Dr. Özgür KAYNAR
Atatürk Üniversitesi, Türkiye
Tolga Karapınar
Fırat Üniversitesi, Türkiye
Ersoy Baydar
Balıkesir Üniversitesi, Türkiye
Armağan Hayırlı
Atatürk Üniversitesi, Türkiye
Özet
Background: Data on accuracy and precision of the Lactate Scout point-of-care (POC) analyzer in ovine medicine are lacking. Objective: The purpose of the study was to assess the reliability of the Lactate Scout in sheep. Materials and Methods: Fifty-seven sheep at varying ages with various diseases were included. Blood lactate concentration in samples collected from the jugular vein was measured immediately on the Lactate Scout. Plasma l-lactate concentration was measured by the Cobas autoanalyzer as the reference method. Data were subjected to Student's t-test, Passing-Bablok regression, and Bland-Altman plot analyses for comparison and assessment of accuracy, precision, and reliability. Results: Plasma l-lactate concentration was consistently lower than blood l-lactate concentration (3.06 ± 0.24 vs 3.3 ± 0.3 mmol/L, P < .0001). There was a positive correlation between plasma and blood l-lactate concentrations (r = .98, P < .0001). The Lactate Scout had 99% accuracy and 98% precision with the reference method. Blood (Y) and plasma (X) l-lactate concentrations were fitted to Y = 0.28 + 1.00 · X, with a residual standard deviation of 0.31 and a negligible deviation from the identity line (P = .93). The bias was fitted to Y = 0.10 + 0.05 · X, with Sy.x of 0.44 (P < .07). Conclusions: The Lactate Scout has high accuracy and precision, with a negligible bias. It is a reliable POC analyzer to assess l-lactate concentration in ovine medicine.
Anahtar Kelimeler
Accuracy | Bias | Lactate meter | Ovine medicine | Precision
Makale Türü Özgün Makale
Makale Alt Türü SSCI, AHCI, SCI, SCI-Exp dergilerinde yayımlanan tam makale
Dergi Adı VETERINARY CLINICAL PATHOLOGY
Dergi ISSN 0275-6382
Dergi Tarandığı Indeksler SCI-Expanded
Makale Dili İngilizce
Basım Tarihi 12-2015
Cilt No 44
Sayı 4
Sayfalar 559 / 563
Doi Numarası 10.1111/vcp.12288