| Yazarlar |
Prof. Dr. Özgür KAYNAR
Atatürk Üniversitesi, Türkiye |
Tolga Karapınar
Fırat Üniversitesi, Türkiye |
|
Ersoy Baydar
Balıkesir Üniversitesi, Türkiye |
|
Armağan Hayırlı
Atatürk Üniversitesi, Türkiye |
| Özet |
| Background: Data on accuracy and precision of the Lactate Scout point-of-care (POC) analyzer in ovine medicine are lacking. Objective: The purpose of the study was to assess the reliability of the Lactate Scout in sheep. Materials and Methods: Fifty-seven sheep at varying ages with various diseases were included. Blood lactate concentration in samples collected from the jugular vein was measured immediately on the Lactate Scout. Plasma l-lactate concentration was measured by the Cobas autoanalyzer as the reference method. Data were subjected to Student's t-test, Passing-Bablok regression, and Bland-Altman plot analyses for comparison and assessment of accuracy, precision, and reliability. Results: Plasma l-lactate concentration was consistently lower than blood l-lactate concentration (3.06 ± 0.24 vs 3.3 ± 0.3 mmol/L, P < .0001). There was a positive correlation between plasma and blood l-lactate concentrations (r = .98, P < .0001). The Lactate Scout had 99% accuracy and 98% precision with the reference method. Blood (Y) and plasma (X) l-lactate concentrations were fitted to Y = 0.28 + 1.00 · X, with a residual standard deviation of 0.31 and a negligible deviation from the identity line (P = .93). The bias was fitted to Y = 0.10 + 0.05 · X, with Sy.x of 0.44 (P < .07). Conclusions: The Lactate Scout has high accuracy and precision, with a negligible bias. It is a reliable POC analyzer to assess l-lactate concentration in ovine medicine. |
| Anahtar Kelimeler |
| Accuracy,bias,lactate meter,precision,ovine medicine |
| Makale Türü | Özgün Makale |
| Makale Alt Türü | SSCI, AHCI, SCI, SCI-Exp dergilerinde yayımlanan tam makale |
| Dergi Adı | VET CLİN PATHOL |
| Dergi ISSN | 0275-6382 |
| Dergi Tarandığı Indeksler | SCI-Expanded |
| Makale Dili | İngilizce |
| Basım Tarihi | 12-2015 |
| Cilt No | 44 |
| Sayı | 4 |
| Sayfalar | 559 / 563 |
| Doi Numarası | 10.1111/v cp.12288 |
