img
Physiological profile of juvenile rats effects of cage size and cage density    
Yazarlar
Ahmet Yıldız
Atatürk Üniversitesi, Türkiye
Armağan Hayırlı
Atatürk Üniversitesi, Türkiye
Zafer Okumuş
Atatürk Üniversitesi, Türkiye
Prof. Dr. Özgür KAYNAR Prof. Dr. Özgür KAYNAR
Atatürk Üniversitesi, Türkiye
Fikrullah Kısa
Özet
Although there is a general consensus that housing conditions affect the well-being of laboratory animals, the ideal cage size and density for housing laboratory rodents has not been established. The authors investigated the effects of cage size and cage density on growth, organ development, metabolic profile, and hemogram in juvenile Sprague-Dawley rats. Larger cages and increased cage density were associated with depressions in body weight and in the weights of several organs. In general, increasing group size and density correlated more strongly with detrimental effects on the growth of females than males, although hemogram values indicated that males are more prone to emotional stress and immune suppression than females in response to increasing group size and crowding.
Anahtar Kelimeler
Makale Türü Özgün Makale
Makale Alt Türü SSCI, AHCI, SCI, SCI-Exp dergilerinde yayımlanan tam makale
Dergi Adı LAB ANIMAL
Dergi ISSN 0093-7355
Dergi Tarandığı Indeksler SCI-Expanded
Makale Dili İngilizce
Basım Tarihi 02-2007
Cilt No 36
Sayı 2
Sayfalar 28 / 38
Doi Numarası 10.1038/laban0207-28
Makale Linki http://www.labanimal.com/laban/doifinder/10.1038/laban0207-28