The Role of Hematologic Parameters in Recurrent Aphthous Stomatitis
Yazarlar (4)
Ümran Öner
Türkiye
Doç. Dr. Fatih ÖNER Kastamonu Üniversitesi, Türkiye
Prof. Dr. Şevki Özdemir Erzincan Binali Yıldırım Üniversitesi, Türkiye
Makale Türü Açık Erişim Özgün Makale (Ulusal alan endekslerinde (TR Dizin, ULAKBİM) yayınlanan tam makale)
Dergi Adı Annals of Medical Research
Dergi ISSN 2636-7688
Dergi Tarandığı Indeksler TR DİZİN
Makale Dili İngilizce Basım Tarihi 02-2021
Cilt / Sayı / Sayfa 28 / 2 / 290–295 DOI 10.5455/annalsmedres.2020.05.495
Makale Linki http://dx.doi.org/10.5455/annalsmedres.2020.05.495
UAK Araştırma Alanları
Kulak Burun Boğaz Hastalıkları
Özet
Aim Recurrent Aphthous Stomatitis (RAS) is one of the most common diseases of oral mucosa characterized by recurrent painful ulcers. Although many factors have been implicated in the etiology of the disease, it has not yet been fully elucidated. We aimed to investigate serum vitamin B12, ferritin, folate, vitamin D, hemoglobin, and thyroid stimulating hormone (TSH) levels in patients with RAS.Materials and Methods The study involved in 60 patients (34 women, 26 men) with idiopathic RAS and 70 healthy volunteers (41 women, 29 men). The serum vitamin B12, ferritin, folate, vitamin D, hemoglobin, and TSH levels of the patients were measured and statistically compared.Results Serum levels of vitamin B12 (204.5 vs. 301.0 pg/ml) and ferritin (31.0 vs. 48.5 ml/ng) were significantly lower and serum level of folate (7.7 vs. 6.7 ng/ml) were significantly higher in the patient group than control group (p<0.05). No significant difference was found between the number of patients and controls who both had abnormal levels of TSH (1.81±1.59 mU/L). There was no significant difference in serum levels of hemoglobin (14.64±1.88 gr/dL) and vitamin D (16.05±13.03 ng/ml) between the groups (p>0.05). No correlations were detected between RAS assessed by family history, mean duration of disease, and frequency of attacks and hematinic deficiencies. Conclusion Vitamin B12 and ferritin deficiency can play a role in the underlying etiology of RAS therefore we suggested the investigation of the vitamin B12 and ferritin status in RAS patients.
Anahtar Kelimeler
BM Sürdürülebilir Kalkınma Amaçları
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The Role of Hematologic Parameters in Recurrent Aphthous Stomatitis

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