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Expression of ADAMTS 1‐4‐8 and placental growth factor in ovary and oviduct during pregnancy in the first trimester    
Yazarlar (4)
Doç. Dr. Musa TATAR Doç. Dr. Musa TATAR
Kastamonu Üniversitesi, Türkiye
Doç. Dr. Kıymet Kübra TÜFEKCİ Doç. Dr. Kıymet Kübra TÜFEKCİ
Kastamonu Üniversitesi, Türkiye
Sema Uslu
Sivas Cumhuriyet Üniversitesi, Türkiye
Jale Öner
Türkiye
Devamını Göster
Özet
A Disintegrin and Metalloprotease Domains with Thrombospondins Motifs (ADAMTS), proteinases responsible for the destruction of extracellular matrix structures, have essential roles in the physiological and pathological processes of the female reproductive system, which is a dynamic structure. This study aimed to evaluate the immunoreactivity of placental growth factor (PLGF) and ADAMTS' (1, ‐4, and ‐8) in the ovary and oviduct during pregnancy in the first trimester. Our findings suggest a predominant role of ADAMTS‐4 and ADAMTS‐8 as proteoglycan‐degrading enzymes from the ADAMTS‐1 in the first trimester. As an angiogenic factor, PLGF showed more immunoreactivity than ADAMTS‐1 in the ovary. This study provides the first evidence that ADAMTS‐4 and ADAMTS‐8 are more expressed in ovarian cells and follicles at different developmental stages during the first trimester of pregnancy than ADAMTS …
Anahtar Kelimeler
Makale Türü Özgün Makale
Makale Alt Türü SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale
Dergi Adı Anatomia, Histologia, Embryologia
Dergi ISSN 0340-2096 Wos Dergi Scopus Dergi
Dergi Tarandığı Indeksler SCI-Expanded
Dergi Grubu Q3
Makale Dili Türkçe
Basım Tarihi 04-2023
Cilt No 52
Sayı 4
Sayfalar 619 / 626
Doi Numarası 10.1111/ahe.12922
Makale Linki http://dx.doi.org/10.1111/ahe.12922