Effects of folic acid on testicular toxicity induced by bisphenol-A in male Wistar rats
Yazarlar (4)
Dr. Öğr. Üyesi Özay Güleş Afyon Kocatepe Üniversitesi, Türkiye
Mustafa Yıldız Türkiye
Zahid Naseer
Doç. Dr. Musa TATAR Türkiye
| Makale Türü | Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale) | ||
| Dergi Adı | BIOTECHNIC & HISTOCHEMISTRY (Q4) | ||
| Dergi ISSN | 1052-0295 Wos Dergi Scopus Dergi | ||
| Dergi Tarandığı Indeksler | SCI-Expanded | ||
| Makale Dili | Türkçe | Basım Tarihi | 02-2019 |
| Cilt / Sayı / Sayfa | 94 / 1 / – | DOI | 10.1080/10520295.2018.1493222 |
| Makale Linki | https://www.tandfonline.com/doi/abs/10.1080/10520295.2018.1493222 | ||
| Özet |
| We investigated the protective effect of the folic acid (FA) against bisphenol-A (BPA) induced toxicity in rat testis. We used four groups of seven adult male Wistar albino rats. The control group was fed corn oil, the BPA group was given BPA, the FA group was given FA and the FA + BPA group was given FA initially followed by BPA 1 h later. The BPA, FA and corn oil were administered by oral gavage for 14 days. At the end of the experiment, testis sections were examined for histological and histomorphometric characteristics. The TUNEL method was used to detect apoptosis and immunohistochemistry was used to examine the distribution of spermatogonial stem cells. Levels of serum testosterone were measured, and sperm viability and morphology were determined. The histological structure of the testis was normal in the control and FA groups. Although the number of TUNEL positive cells/tubule increased, the … |
| Anahtar Kelimeler |
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| Google Scholar | 52 |