Yazarlar (4) |
![]() Kastamonu Üniversitesi, Türkiye |
![]() Kastamonu Üniversitesi, Türkiye |
![]() Alanya Alaaddin Keykubat Üniversitesi, Türkiye |
![]() Süleyman Demirel Üniversitesi, Türkiye |
Özet |
It has been well known that estrogen has antioxidant role on cardiovascular, gastrointestinal and neurological systems. Estrogen deficiency may active the channels although supplementation of estrogen may inhibit the channels via its antioxidant properties and support antioxidant levels in the neurons. Raloxifene and tamoxifen are selective estrogen receptor modulators (SERMs). They exert tissue-selective agonist-antagonist effects on estrogen receptors. The antioxidant properties of raloxifene and tamoxifen may also have a regulator role in the brain of ovariectomized rats. We aimed to investigate the effects of estradiol, raloxifene and tamoxifen on the oxidative stress in brain of ovariectomized (OVX) rats. Forty female Wister Albino rats were divided into five groups: First group was used as control. Second group used as ovariectomized. Third, fourth and five groups received estrogen, tamoxifen and raloxifene … |
Anahtar Kelimeler |
Makale Türü | Diğer (Teknik, not, yorum, vaka takdimi, editöre mektup, özet, kitap krıtiği, araştırma notu, bilirkişi raporu ve benzeri) |
Makale Alt Türü | SCOPUS dergilerinde yayınlanan teknik not, editöre mektup, tartışma, vaka takdimi ve özet türünden makale |
Dergi Adı | Journal of Cellular Neuroscience and Oxidative Stress |
Dergi ISSN | 2149-7222 Scopus Dergi |
Dergi Tarandığı Indeksler | SCOPUS |
Makale Dili | İngilizce |
Basım Tarihi | 03-2015 |
Cilt No | 7 |
Sayı | 1 |
Sayfalar | 426 / |
Makale Linki | https://dergipark.org.tr/tr/pub/jcnos/issue/47994 |