Yazarlar (4) |
![]() Kastamonu Üniversitesi, Türkiye |
![]() Kastamonu Üniversitesi, Türkiye |
![]() Alanya Alaaddin Keykubat Üniversitesi, Türkiye |
![]() Süleyman Demirel Üniversitesi, Türkiye |
Özet |
In the postmenopausal period, the decrease in ovarian hormones can influence inflammation and oxidative stress in many tissues. Estrogen has antioxidant role in all the physiological systems and its deficiency may active the channels via antioxidant properties of estrogen and support antioxidant levels in various tissues. Tamoxifen and raloksifen are selective estrogen receptor modulators (SERMs). They exert tissue-selective agonist-antagonist effects on estrogen receptors. The antioxidant properties of tamoxifen and raloxifene may also have a regulator role on oxidative stress in liver, heart and kidney tissues of ovariectomized rats. We aimed to investigate the effects of estradiol, raloxifene and tamoxifen on the oxidative stress in liver, heart and kidney of ovariectomized rats. Two weeks after ovariectomy, female Wistar Albino rats (n= 40) were equally divided into five groups as control group, ovariectomized … |
Anahtar Kelimeler |
Makale Türü | Diğer (Teknik, not, yorum, vaka takdimi, editöre mektup, özet, kitap krıtiği, araştırma notu, bilirkişi raporu ve benzeri) |
Makale Alt Türü | SCOPUS dergilerinde yayınlanan teknik not, editöre mektup, tartışma, vaka takdimi ve özet türünden makale |
Dergi Adı | Journal of Cellular Neuroscience and Oxidative Stress |
Dergi ISSN | 2149-7222 Scopus Dergi |
Dergi Tarandığı Indeksler | SCOPUS |
Makale Dili | İngilizce |
Basım Tarihi | 01-2015 |
Cilt No | 7 |
Sayı | 1 |
Sayfalar | 428 / |
Makale Linki | https://dergipark.org.tr/tr/pub/jcnos/issue/47994 |