Dietary effect of grape (Vitis vinifera) seed extract mitigates hepatic disorders caused by oxidized fish oil in rainbow trout (Oncorhynchus mykiss)
 
Yazarlar (7)
Doç. Dr. Funda TERZİ Kastamonu Üniversitesi, Türkiye
Doç. Dr. Beste DEMİRCİ Kastamonu Üniversitesi, Türkiye
Dr. Öğr. Üyesi Süleyman YÜKSEL Kastamonu Üniversitesi, Türkiye
Arş. Gör. Dr. Çağatay SALUM Kastamonu Üniversitesi, Türkiye
Doç. Dr. Hüseyin Serkan Erol Kastamonu Üniversitesi, Türkiye
Prof. Dr. Osman Sabri KESBİÇ Kastamonu Üniversitesi, Türkiye
Makale Türü Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale)
Dergi Adı FISH PHYSIOLOGY AND BIOCHEMISTRY (Q1)
Dergi ISSN 0920-1742 Wos Dergi Scopus Dergi
Dergi Tarandığı Indeksler SCI-Expanded
Makale Dili Türkçe Basım Tarihi 06-2023
Cilt / Sayı / Sayfa 49 / 3 / 441–454 DOI 10.1007/s10695-023-01193-6
Makale Linki http://dx.doi.org/10.1007/s10695-023-01193-6
Özet
The major goal of this study was to determine the effect of grape seed extract (GSE) on liver damage in rainbow trout (Oncorhynchus mykiss) that was caused by the consumption of dietary oxidized fish oil (OFO). Rainbow trout were fed six different experimental diets coded OX-GSE 0 (OFO diet), OX-GSE 1 (OFO and 0.1% GSE), OX-GSE 3 (OFO and 0.3% GSE), GSE 0 (fresh fish oil and 0.0% GSE), GSE 1 (fresh fish oil and 0.1% GSE), and GSE 3 (fresh fish oil and 0.3% GSE) for 30 days. The lowest % hepatosomatic index (HSI) result was calculated in fish fed with OX-GSE 0 and the highest HSI was determined in fish fed with GSE 1 diets (p < 0.05). Histopathologically, hydropic degeneration in hepatocytes significantly increased OX-GSE 0 and GSE 3 compared to GSE 1 diets (p < 0.05). Deposition of lipid droplets in hepatocytes was significantly increased in OX-GSE 0 and OX-GSE 3 groups than others (p < …
Anahtar Kelimeler
Antioxidant capacity | Grape seed extract | Liver biochemistry | Oxidative stress | Oxidized oil