Molecular analysis of the env, LTR, and pX regions of bovine leukemia virus in dairy cattle of Türkiye
Yazarlar (2)
Dr. Öğr. Üyesi Selda DURAN YELKEN Kastamonu Üniversitesi, Türkiye
Prof. Dr. Feray Alkan Ankara Üniversitesi, Türkiye
| Makale Türü | Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale) | ||
| Dergi Adı | Virus Genes (Q3) | ||
| Dergi ISSN | 0920-8569 Wos Dergi Scopus Dergi | ||
| Dergi Tarandığı Indeksler | SCI-Expanded | ||
| Makale Dili | Türkçe | Basım Tarihi | 02-2024 |
| Cilt / Sayı / Sayfa | 60 / 2 / 173–185 | DOI | 10.1007/s11262-024-02058-7 |
| Makale Linki | http://dx.doi.org/10.1007/s11262-024-02058-7 | ||
| Özet |
| Bovine leukemia virus is a retrovirus that causes enzootic bovine leukosis and is associated with global economic losses in the livestock industry. The aim of this study was to investigate the genotype determination of BLVs from cattle housed in 6 different farms in Türkiye and the characterization of their LTR and pX (tax, rex, R3, and G4 gene) regions. For this purpose, blood samples from 48 cattle infected with BLV were used. The phylogenetic analysis based on the env gene sequences revealed that all BLVs were clustered in genotype 1 (G1), and the sequences of the LTR (n = 48) and the pX region (n = 33) of BLVs were obtained. Also, analysis of these nucleic acid and amino acid sequences allowed assessments similar to those reported in earlier studies to be relevant to transactivation and pathogenesis. This study reports the molecular analysis of the LTR and pX region of BLVs in Türkiye for the first time. |
| Anahtar Kelimeler |
| Bovine leukemia virus (BLV) | Env gene | LTR region | Molecular analysis | pX region |
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| Web of Science | 2 |
| Scopus | 2 |