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Use of metabolomics tools in the evaluation of the fattening performance of lambs       
Yazarlar
Mücahit Kahraman
Harran Üniversitesi, Türkiye
Aydın Daş
Harran Üniversitesi, Türkiye
Dr. Öğr. Üyesi Gülşah GÜNGÖREN
Kastamonu Üniversitesi, Türkiye
Besime Doğan Daş
Harran Üniversitesi, Türkiye
Hamza Yalçin
Harran Üniversitesi, Türkiye
İsmail Koyuncu
Türkiye
Şükrü Akmeşe
Türkiye
Özet
This study aimed to determine the metabolomic characteristics associated with the fattening performance of the Awassi lamb breed under intensive fattening for 90 days. Twenty-four lambs were used in the research. The lambs were divided into two groups according to their fattening performance (good fattening performance, n = 12, and poor fattening performance, n = 12), and their metabolomic properties were evaluated. The differences between the two research groups in the amino acids of alloisoleucine, aspartic acid, histidine, hydroxylysine, isoleucine, lysine, methionine, phenylalanine, tryptophan, valine, and 1-methylhistidine were found to be statistically significant (P ≤ 0.001). Moderately significant negative correlations were found between daily concentrate feed intake and 3-methylhistidine (r = -0.469; P = 0.021), hydroxylysine (r = -0.408; P = 0.048), and serotonin (r = -0.467; P = 0.021); as well as between the average daily weight gain (ADWG) and alloisoleucine (r = -0.528; P = 0.008), 3-methylhistidine (r = -0.440; P = 0.032), and hydroxylysine (r = -0.577; P = 0.003). A moderate positive correlation was found between hydroxyisovalerylcarnitine and ADWG (r = 0.476; P = 0.019), and a negative correlation was found between hydroxyisovalerylcarnitine and the feed conversion ratio (r = -0.430; P = 0.036). Pathway analysis revealed that the most important biological pathway was the phenylalanine, tyrosine, and tryptophan biosynthesis pathway. The results of the research reveal the potential for plasma free amino acid and carnitine profiles to be used as candidate biomarkers in the evaluation of fattening performance in lambs.
Anahtar Kelimeler
amino acid,carnitine,fattening performance,metabolomics,lamb
Makale Türü Özgün Makale
Makale Alt Türü SSCI, AHCI, SCI, SCI-Exp dergilerinde yayımlanan tam makale
Dergi Adı Medycyna Weterynaryjna-Veterinary Medicine-Science and Practice
Dergi ISSN 0025-8628
Dergi Tarandığı Indeksler SCI-Expanded
Dergi Grubu Q4
Makale Dili İngilizce
Basım Tarihi 07-2022
Cilt No 78
Sayı 9
Sayfalar 461 / 467
Doi Numarası 10.21521/mw.6697
Makale Linki DOI: dx.doi.org/10.21521/mw.6697
BM Sürdürülebilir Kalkınma Amaçları
Atıf Sayıları
Use of metabolomics tools in the evaluation of the fattening performance of lambs

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