Use of metabolomics tools in the evaluation of the fattening performance of lambs
Yazarlar (7)
Doç. Dr. Mücahit Kahraman Harran Üniversitesi, Türkiye
Aydın Daş Harran Üniversitesi, Türkiye
Dr. Öğr. Üyesi Gülşah GÜNGÖREN Kastamonu Üniversitesi, Türkiye
Besime Doğan Daş Harran Üniversitesi, Türkiye
Hamza Yalçin Harran Üniversitesi, Türkiye
Prof. Dr. İsmail Koyuncu Harran University, Faculty Of Medicine, Türkiye
Şükrü Akmeşe Harran Üniversitesi, Türkiye
Makale Türü Açık Erişim Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale)
Dergi Adı Medycyna Weterynaryjna (Q4)
Dergi ISSN 0025-8628 Wos Dergi Scopus Dergi
Dergi Tarandığı Indeksler SCI-Expanded
Makale Dili İngilizce Basım Tarihi 07-2022
Cilt / Sayı / Sayfa 78 / 9 / 461–467 DOI 10.21521/mw.6697
Makale Linki DOI: dx.doi.org/10.21521/mw.6697
Özet
This study aimed to determine the metabolomic characteristics associated with the fattening performance of the Awassi lamb breed under intensive fattening for 90 days. Twenty-four lambs were used in the research. The lambs were divided into two groups according to their fattening performance (good fattening performance, n = 12, and poor fattening performance, n = 12), and their metabolomic properties were evaluated. The differences between the two research groups in the amino acids of alloisoleucine, aspartic acid, histidine, hydroxylysine, isoleucine, lysine, methionine, phenylalanine, tryptophan, valine, and 1-methylhistidine were found to be statistically significant (P ≤ 0.001). Moderately significant negative correlations were found between daily concentrate feed intake and 3-methylhistidine (r = −0.469; P = 0.021), hydroxylysine (r = −0.408; P = 0.048), and serotonin (r= −0.467; P = 0.021); as well as between the average daily weight gain (ADWG) and alloisoleucine (r = −0.528; P = 0.008), 3-methylhistidine (r = −0.440; P = 0.032), and hydroxylysine (r = −0.577; P = 0.003). A moderate positive correlation was found between hydroxyisovalerylcarnitine and ADWG (r = 0.476; P = 0.019), and a negative correlation was found between hydroxyisovalerylcarnitine and the feed conversion ratio (r = −0.430; P = 0.036). Pathway analysis revealed that the most important biological pathway was the phenylalanine, tyrosine, and tryptophan biosynthesis pathway. The results of the research reveal the potential for plasma free amino acid and carnitine profiles to be used as candidate biomarkers in the evaluation of fattening performance in lambs.
Anahtar Kelimeler
amino acid | carnitine | fattening performance | lamb | metabolomics
BM Sürdürülebilir Kalkınma Amaçları
Atıf Sayıları
Web of Science 3
Scopus 3
Google Scholar 5
Use of metabolomics tools in the evaluation of the fattening performance of lambs

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