Age and frailty are independently associated with increased COVID-19 mortality and increased care needs in survivors: results of an international multi-centre study
Yazarlar (11)
Mertcan Akçay
Recayi Çapoğlu
Türkiye
Hakan Demir
Emre Gönüllü
Türkiye
Ali Muhtaroğlu
Giresun Üniversitesi, Türkiye
Merve Yiğit
Makale Türü Açık Erişim Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale)
Dergi Adı AGE AND AGEING (Q1)
Dergi ISSN 0002-0729 Dergi Bilgileri (2021)
Dergi Tarandığı Indeksler SCI-Expanded
Makale Dili İngilizce Basım Tarihi 05-2021
Kabul Tarihi Yayınlanma Tarihi 05-02-2021
Cilt / Sayı / Sayfa 50 / 3 / 617–630 DOI 10.1093/ageing/afab026
Makale Linki http://dx.doi.org/10.1093/ageing/afab026
UAK Araştırma Alanları
Sağlık Bilimleri
Özet
Introduction Increased mortality has been demonstrated in older adults with coronavirus disease 2019 (COVID-19), but the effect of frailty has been unclear. Methods This multi-centre cohort study involved patients aged 18 years and older hospitalised with COVID-19, using routinely collected data. We used Cox regression analysis to assess the impact of age, frailty and delirium on the risk of inpatient mortality, adjusting for sex, illness severity, inflammation and co-morbidities. We used ordinal logistic regression analysis to assess the impact of age, Clinical Frailty Scale (CFS) and delirium on risk of increased care requirements on discharge, adjusting for the same variables. Results Data from 5,711 patients from 55 hospitals in 12 countries were included (median age 74, interquartile range [IQR] 54–83; 55.2% male). The risk of death increased …
Anahtar Kelimeler
frailty | COVID-19 | mortality | transitions of care | delirium