Surface chemistry dependent toxicity of inorganic nanostructure glycoconjugates on bacterial cells and cancer cell lines
Yazarlar (15)
Sedanur Sancak
Kastamonu Üniversitesi, Türkiye
Prof. Dr. İdris YAZGAN Kastamonu Üniversitesi, Türkiye
Dr. Öğr. Üyesi Aslı Uğurlu Bayarslan Kastamonu Üniversitesi, Türkiye
Doç. Dr. Adnan Ayna Bingöl Üniversitesi, Türkiye
Senanur Evecen Kastamonu Üniversitesi, Türkiye
Zehra Taşdelen
Kastamonu Üniversitesi, Türkiye
Doç. Dr. Abdurrahman Gümüş Izmir Yüksek Teknoloji Enstitüsü, Türkiye
Hamide Ayçin Sönmez Kastamonu Üniversitesi, Türkiye
Dr. Öğr. Üyesi Mehmet Ali Demir Kastamonu Üniversitesi, Türkiye
Sosin Demir
Kastamonu Üniversitesi, Türkiye
Fatma Bakar
Kastamonu Üniversitesi, Türkiye
Doç. Dr. Hafize Dilek Tepe Manisa Celâl Bayar Üniversitesi, Türkiye
Kaja Kasemets
National Institute Of Chemical Physics And Biophysics, Estonya
Maarja Otsus
National Institute Of Chemical Physics And Biophysics, Estonya
Prof. Dr. Talip ÇETER Kastamonu Üniversitesi, Türkiye
Makale Türü Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale)
Dergi Adı Journal of Drug Delivery Science and Technology (Q1)
Dergi ISSN 1773-2247 Wos Dergi Scopus Dergi
Dergi Tarandığı Indeksler SCI-Expanded
Makale Dili İngilizce Basım Tarihi 01-2023
Cilt / Sayı / Sayfa 79 / 1 / 1–11 DOI 10.1016/j.jddst.2022.104054
Makale Linki http://dx.doi.org/10.1016/j.jddst.2022.104054
UAK Araştırma Alanları
Bitki Morfolojisi ve Anatomisi
Özet
Surface functionalized nanostructures have outstanding potential in biological applications owing to their target-specific design. In this study, we utilized laboratory synthesized carbohydrate-derivatives (i.e., galactose, mannose, lactose, and cellobiose derivatives) for aqueous one-pot synthesis of gold (Au) and silver (Ag) nanostructure glycoconjugates (NSs), and iron metal-organic framework glycoconjugates (FeMOFs). This work aims to test whether differences in the surface chemistry of the inorganic nanostructures play roles in revealing their toxicities towards bacterial cells and cancerous cell lines. As of the first step, biological activity of AuNSs, AgNSs, and FeMOFs were tested against a variety of gram (−) and gram (+) bacterial strains, where AgNSs possessed moderate to high antibacterial activities against all the tested bacterial strains, while AuNSs and FeMOFs showed their bacterial toxicity mostly …
Anahtar Kelimeler
And anticancer | Antibacterial | Carbohydrate derivatives | Nanostructure glycoconjugates