A new pollen derived microcarrier for Pantoprazole delivery
Yazarlar (5)
Doç. Dr. Lalehan Akyüz Aksaray Üniversitesi, Türkiye
Prof. Dr. İdris Sargın Aksaray Üniversitesi, Türkiye
Prof. Dr. Murat Kaya Aksaray Üniversitesi, Türkiye
Prof. Dr. Talip ÇETER Kastamonu Üniversitesi, Türkiye
Prof. Dr. Ilgaz Akata Ankara Üniversitesi, Türkiye
| Makale Türü | Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale) | ||
| Dergi Adı | Materials Science and Engineering C (Q1) | ||
| Dergi ISSN | 0928-4931 Wos Dergi Scopus Dergi | ||
| Dergi Tarandığı Indeksler | SCI-Expanded | ||
| Makale Dili | İngilizce | Basım Tarihi | 02-2017 |
| Cilt / Sayı / Sayfa | 71 / 1 / 937–942 | DOI | 10.1016/j.msec.2016.11.009 |
| Makale Linki | http://www.sciencedirect.com/science/article/pii/S0928493116309845 | ||
| UAK Araştırma Alanları |
Bitki Morfolojisi ve Anatomisi
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| Özet |
| Plant-derived carriers have emerged as promising materials for drug encapsulation. Especially, sporopollenin microcapsules extracted from diverse pollen species have been proved to be effective drug carriers due to their biocompatibility, homogeneity in size, resistance to harsh chemical conditions and high thermal stability. Here in this study, sporopollenin microcapsules were isolated successfully from the pollens of a common tree (Corylus avellana, the European hazelnut) and used as a carrier for pantoprazole (PaNa) (a proton pump inhibitor). The drug entrapment efficiency was recorded as 29.81%. SEM micrographs clearly showed the drug was loaded into the microcapsules through the apertures of microcapsule and also some drugs were adsorbed on the surface of microcapsules. FT-IR spectra analysis confirmed the drug loading. Thermogravimetric analysis revealed that thermal stability of PaNa was … |
| Anahtar Kelimeler |
| Colon delivery | Delayed-release | Hazelnut pollen | Kinetics | Proton pump inhibitor |
Science Direct
A new pollen derived microcarrier for Pantoprazole delivery
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| Web of Science | 38 |
| Scopus | 41 |
| Google Scholar | 53 |