Yazarlar |
Muhammad Mujtaba
|
Idrıs Sargın
|
Lalehan Akyüz
Aksaray Üniversitesi, Türkiye |
Prof. Dr. Talip ÇETER
Kastamonu Üniversitesi, Türkiye |
Murat Kaya
Aksaray Üniversitesi, Türkiye |
Özet |
Sporopollenin microcages were produced from the pollens of Platanus orientalis. Paracetamol was loaded into the microcages. Pollen, sporopollenin, paracetamol and paracetamol-loaded sporopollenin microcages were characterized with FT-IR, TGA and SEM. The analytical analyses demonstrated that sporopollenin microcages were structurally intact, highly reticulated and thermally stable. The loading efficiency of the sporopollenin microcages was found to be 8.2% using the passive loading technique and 23.7% via evaporating loading technique. In vitro release and kinetics studies were performed to test the suitability of sporopollenin microcages for loading. These studies revealed that sporopollenin from P. orientalis can be suggested as a suitable carrier for drug loading and controlled release studies. |
Anahtar Kelimeler |
Acetaminophen | Drug delivery | Microcapsule | Release kinetics |
Makale Türü | Özgün Makale |
Makale Alt Türü | SSCI, AHCI, SCI, SCI-Exp dergilerinde yayımlanan tam makale |
Dergi Adı | MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS |
Dergi ISSN | 0928-4931 |
Dergi Tarandığı Indeksler | SCOPUS, SCI-Exp |
Dergi Grubu | Q1 |
Makale Dili | İngilizce |
Basım Tarihi | 08-2017 |
Cilt No | 77 |
Sayı | 1 |
Sayfalar | 263 / 270 |
Doi Numarası | 10.1016/j.msec.2017.02.176 |