| Makale Türü | Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale) | ||
| Dergi Adı | Biotechnic and Histochemistry (Q4) | ||
| Dergi ISSN | 1052-0295 Dergi Bilgileri (2023) | ||
| Dergi Tarandığı Indeksler | SCI-Expanded | ||
| Makale Dili | Türkçe | Basım Tarihi | 05-2023 |
| Kabul Tarihi | – | Yayınlanma Tarihi | 22-02-2023 |
| Cilt / Sayı / Sayfa | 98 / 4 / 255–266 | DOI | 10.1080/10520295.2023.2176923 |
| Makale Linki | https://www.tandfonline.com/doi/full/10.1080/10520295.2023.2176923 | ||
| UAK Araştırma Alanları |
Veteriner Fizyolojisi
|
||
| Özet |
| Increased pro-inflammatory cytokines and oxidative stress contribute to the pathophysiology of ulcerative colitis (UC). Inula viscosa is a plant with antioxidant and anti-inflammatory properties. We investigated the effect of an ethanolic extract of I. viscosa on an experimental UC model created using acetic acid. Rats were divided into four groups of eight: group 1, control; group 2, 3% acetic acid group; group 3, 100 mg/kg sulfasalazine + 3% acetic acid group; group 4, 400 mg/kg I. viscosa + 3% acetic acid. I. viscosa and sulfasalazine were administered by oral gavage and 3% acetic acid was administered per rectum. We found that I. viscosa treatment decreased colon malondialdehyde, tumor necrosis factor-α, interleukin-1 beta and nuclear factor kappa B levels; it increased reduced glutathione, nuclear factor erythroid 2–related factor 2, heme oxygenase-1 and kelch-like ECH-associated protein 1 levels and … |
| Anahtar Kelimeler |
| Acetic acid | antioxidant | inflammation | Inula viscosa | rats | ulcerative colitis |
| Atıf Sayıları | |
| Web of Science | 5 |
| Scopus | 5 |
| Google Scholar | 6 |
| Dergi Adı | BIOTECHNIC & HISTOCHEMISTRY |
| Kısa Adı | BIOTECH HISTOCHEM |
| Yayıncı | TAYLOR & FRANCIS LTD |
| Açık Erişim | Hayır |
| ISSN | 1052-0295 |
| E-ISSN | 1473-7760 |
| Wos Quartile | Q4 |
| Scopus Quartile | Q2 |
| Tarandığı Indeksler | SCIE , Scopus |
| WoS Kategoriler | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | CELL BIOLOGY |
| Scopus Kategoriler | MEDICAL LABORATORY TECHNOLOGY | HISTOLOGY | MEDICINE (MISCELLANEOUS) |