| Yazarlar |
Bekir Akgun
|
|
Sait Ozturk
|
Dr. Öğr. Üyesi İsmail TAŞKENT
Kastamonu Üniversitesi |
|
Mehmet Besir Surme
|
|
Fatih Serhat Erol
|
|
Hanefi Yildirim
|
| Özet |
| AIM: To evaluate the preoperative and postoperative 6th month mean apparent diffusion coefficient (ADC) values of the cerebellar tonsils and bulbus in patients with Chiari Malformation Type I (CMI), and to compare the results with healthy controls. MATERIAL and METHODS: We included 15 patients with CMI who underwent suboccipital decompression, upper cervical laminectomy, and duraplasty surgery, and compared them with 10 healthy individuals. Three regions of interest were placed, one each in the cerebellar tonsils and one in the bulbus. The mean ADC values were measured separately in each region. RESULTS: Among the patients, mean ADC values were significantly decreased after surgery compared with before surgery. The mean ADC values before surgery were significantly higher for patients than for controls; however, although the mean ADC values were slightly higher after surgery for patients than for controls, the differences were not significant. Thus, after surgical intervention, ADC values in patients with CMI became close to those of normal individuals. CONCLUSION: The increased ADC values in patients with CMI before surgery implied that not only morphologic changes but also increased diffusivity may play a key role in the pathophysiology and clinical presentation of the disease. Decompression surgery can produce favorable diffusional alterations. |
| Anahtar Kelimeler |
| Apparent diffusion coefficient,Chiari malformation type 1,Diffusion-weighted imaging,Suboccipital decompression |
| Makale Türü | Özgün Makale |
| Makale Alt Türü | ESCI dergilerinde yayımlanan tam makale |
| Dergi Adı | TURKISH NEUROSURGERY |
| Dergi ISSN | 1019-5149 |
| Makale Dili | İngilizce |
| Basım Tarihi | 1-2018 |
| Cilt No | 28 |
| Sayı | 5 |
| Sayfalar | 710 / 715 |
| Doi Numarası | 10.5137/1019-5149.JTN.20326-17.1 |
| Atıf Sayıları | |
| WoS | 1 |
| SCOPUS | 1 |
