Investigation of antifungal activity of ononis spinosa L ASH used for the therapy of skin infections as folk remedies
Yazarlar (3)
Prof. Dr. Ergin Murat ALTUNER Kastamonu Üniversitesi, Türkiye
Prof. Dr. Talip ÇETER Kastamonu Üniversitesi, Türkiye
Cemil Lşlek
Niğde Ömer Halisdemir University, Türkiye
Niğde Ömer Halisdemir University, Türkiye
| Makale Türü | Özgün Makale (SCOPUS dergilerinde yayınlanan tam makale) | ||
| Dergi Adı | Mikrobiyoloji Bulteni | ||
| Dergi ISSN | 0374-9096 Wos Dergi Scopus Dergi | ||
| Dergi Tarandığı Indeksler | SCI-Exp, SCOPUS, Biological Abstracts, Biosis Previews, Biosis Selective Coverage Shared, Curation, Essential Science Indicators, Pdf2xml, Pdf2xml, Reference Master, Sophia, Web Of Science Expanded | ||
| Makale Dili | İngilizce | Basım Tarihi | 10-2010 |
| Cilt / Sayı / Sayfa | 44 / 4 / 633–639 | DOI | – |
| Makale Linki | https://publons.com/wos-op/publon/27420265/ | ||
| UAK Araştırma Alanları |
Fen Bilimleri ve Matematik
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| Özet |
| Traditional folk remedies used for centuries come up focus of interest in recent years, due to the trend of use of herb-derived natural products. In addition, increasing morbidity and mortality rates of opportunistic fungal infections and accelerating antifungal resistance rates of fungi lead to the use of alternative therapies with herb-derived preparations as novel antifungals. Ononis spinosa L.(spiny restharrow), which is classified in Leguminosae family, is one of the plants used in herbal medicine as folk remedies for the treatment of skin lesions and/or infections as well as many other disorders. Antibacterial, antifungal, anti-inflammatory and analgesic effects of Ononis spinosa (OS) have already been supported by different studies. The roots and aerial sections of OS are the mainly employed parts for application, however local communities inhabiting at southeastern parts of Anatolia, Turkey, employ the ashes of OS widely to heal the skin infections. There have been no reports about the antifungal activity of OS ashes as far as the current literature is concerned. The aim of this study was to investigate the antifungal activity of ashes of OS, collected from a rural area located at Southeast Anatolia. Ashes of OS have been obtained by burning the plant samples at 400 C, and extracted in sterile distilled water and ethanol. The efficacy of aqueous and ethanol extracts of OS ashes were tested against 10 fungi, of which one was a Candida albicans standard strain (ATCC 95071) and the others were clinical isolates (C. albicans, Candida glabrata, Candida tropicalis, Candida krusei, Candida guilliermondii, Candida parapsilosis, Candida pelliculosa … |
| Anahtar Kelimeler |
| Antifungal activity | Disc diffusion test | MFC | MIC | Ononis spinosa L. ash |
