| Yazarlar |
Doç. Dr. Adem Yavuz SÖNMEZ
Kastamonu Üniversitesi, Türkiye |
Doç. Dr. Soner BİLEN
Kastamonu Üniversitesi, Türkiye |
Arş. Gör. Dr. Yiğit TAŞTAN
Kastamonu Üniversitesi, Türkiye |
Arş. Gör. Dr. Osman Nezih KENANOĞLU
Kastamonu Üniversitesi, Türkiye |
Doç. Dr. Ertuğrul TERZİ
Kastamonu Üniversitesi, Türkiye |
| Özet |
| The potential dietary utilization of Astragalus caudiculosus (AC) in rainbow trout (Oncorhynchus mykiss) was investigated. Four different fish groups (control, AC1, AC2.5, and AC5) were assigned and received the AC-containing diet for 90 days at the rates of 0, 1, 2.5, and 5%, respectively. Results indicated that the growth performance of the AC supplemented fish improved significantly (P < 0.05). Among non-specific immune parameters examined, while lysozyme activity of the AC supplemented fish increased (P < 0.05), oxidative radical production decreased in AC1 and AC2.5 fish groups (P < 0.05) but did not differ in the AC5 group (P > 0.05) compared to the control. Moreover, myeloperoxidase activity was not affected by the AC supplementation (P > 0.05). All pro-inflammatory and anti-inflammatory cytokine gene expressions, except IL-1β, were up-regulated, especially in the fish groups fed with 2.5 and 5% AC supplemented feed (P < 0.05). AC administration caused an elevation in GPx and G6PDH activities, and a decrease in SOD, CAT, and lipid peroxidation (P < 0.05). Overall, AC extract was found to improve the growth, antioxidant status, and immune response of the fish. |
| Anahtar Kelimeler |
| Astragalus | Cytokine gene expression | Feed additive | Growth performance | Immune response | Rainbow trout |
| Makale Türü | Özgün Makale |
| Makale Alt Türü | SSCI, AHCI, SCI, SCI-Exp dergilerinde yayımlanan tam makale |
| Dergi Adı | Fish & Shellfish Immunology |
| Dergi ISSN | 1050-4648 |
| Dergi Tarandığı Indeksler | SCI-Expanded |
| Dergi Grubu | Q1 |
| Makale Dili | İngilizce |
| Basım Tarihi | 02-2022 |
| Cilt No | 122 |
| Sayı | 1 |
| Sayfalar | 366 / 375 |
| Doi Numarası | 10.1016/j.fsi.2022.02.031 |
| Makale Linki | http://dx.doi.org/10.1016/j.fsi.2022.02.031 |
| Atıf Sayıları | |
| SCOPUS | 11 |
