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In acute organophosphate poisoning, the efficacy of hemoperfusion on clinical status and mortality   
Yazarlar
Levent Altintop
Ondokuz Mayis Üniversitesi, Turkey
Dursun Aygun
Ondokuz Mayis Üniversitesi, Turkey
Havva Sahin
Ondokuz Mayis Üniversitesi, Turkey
Zahide Doganay
Ondokuz Mayis Üniversitesi, Turkey
Hakan Guven
Ondokuz Mayis Üniversitesi, Turkey
Yüksel Bek
Ondokuz Mayis Üniversitesi, Turkey
Tekin Akpolat
Ondokuz Mayis Üniversitesi, Turkey
Özet
The aims of this study were to report experience in patients with organophosphate poisoning (OPP) and to discuss the potential role for hemoperfusion (HP) in the management of severe OPP. At the emergency service of a university hospital, 52 patients with acute OPP were included in this retrospective study. The patients were divided into 2 groups (Group 1, severe poisoning, n = 25; and Group 2, mild poisoning, n = 27). All patients with mild OPP survived. Seven patients (28%) of the 25 with severe OPP died. This study supports previous data documenting that HP is unnecessary in the management of mild OPP. Although there was not a control group (severe poisoning without HP treatment) in this study, experience suggests that HP can be useful in severe cases. Reports from centers having experience with severe OPP can help clarify this controversial issue. Randomized controlled (prospective) studies investigating the possible beneficial effects of HP on patient survival in patients with severe OPP with control group are needed. Copyright © 2005 Sage Publications.
Anahtar Kelimeler
Hemoperfusion | Management | Severe organophosphate poisoning
Makale Türü Özgün Makale
Makale Alt Türü SCOPUS dergilerinde yayımlanan tam makale
Dergi Adı Journal of Intensive Care Medicine
Dergi ISSN 0885-0666
Makale Dili İngilizce
Basım Tarihi 12-2005
Cilt No 20
Sayı 6
Sayfalar 298 / 302
Doi Numarası 10.1177/0885066605279834