Diagnostic value of procalcitonin levels as an early indicator of sepsis
 
Yazarlar (8)
Arş. Gör. Hakan Guven Ondokuz Mayis Üniversitesi, Türkiye
Levent Altintop
Ondokuz Mayis Üniversitesi, Türkiye
Ahmet Baydin Ondokuz Mayis Üniversitesi, Türkiye
Saban Esen Ondokuz Mayis Üniversitesi, Türkiye
Prof. Dr. Dursun Aygun Ondokuz Mayis Üniversitesi, Türkiye
Murat Hokelek Ondokuz Mayis Üniversitesi, Türkiye
Prof. Dr. Zahide DOĞANAY Ondokuz Mayis Üniversitesi, Türkiye
Yuksel Bek Ondokuz Mayis Üniversitesi, Türkiye
Makale Türü Özgün Makale (SCOPUS dergilerinde yayınlanan tam makale)
Dergi Adı American Journal of Emergency Medicine
Dergi ISSN 0735-6757 Wos Dergi Scopus Dergi
Makale Dili İngilizce Basım Tarihi 01-2002
Cilt / Sayı / Sayfa 20 / 3 / 202–206 DOI 10.1053/ajem.2002.33005
Özet
Researchers and clinicians have been investigating and implementing various methods of early diagnosis for sepsis before documentation of infection. The aim of this study was to outline the efficiency of procalcitonin (PCT), C-reactive protein (CRP), and white blood cell count (WBC) in determining the early diagnosis of sepsis in the emergency department. Between January 1999 and September 2000, 34 patients with signs of systemic inflammatory response syndrome (SIRS) were enrolled in the study. The patients were divided into 2 groups according to nonsuspected sepsis and suspected sepsis clinically. Admission PCT was significantly higher in suspected sepsis group (median 68.7 μg/L; lower [L] = 15.24 μg/L, upper [U] = 120.54 μg/L) compared with the unsuspected sepsis group (.23 μg/L; L = .10 μg/L, U = .44 μg/L). PCT values were compared with WBC and CRP levels. Predictive accuracy for sepsis expressed as area under the receiver operating characteristic (ROC) curve was .88 for PCT, .44 for WBC, and .34 for CRP. PCT can probably be used as a predictive marker in bacterial infections in emergency departments. Copyright 2002, Elsevier Science (USA). All rights reserved.
Anahtar Kelimeler
C-reactive protein | Emergency departments | Procalcitonin | Sepsis
Science Direct
BM Sürdürülebilir Kalkınma Amaçları
Atıf Sayıları
Scopus 69
Diagnostic value of procalcitonin levels as an early indicator of sepsis

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