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Diagnostic value of procalcitonin levels as an early indicator of sepsis   
Yazarlar
Hakan Guven
Ondokuz Mayis Üniversitesi, Turkey
Levent Altintop
Ondokuz Mayis Üniversitesi, Turkey
Ahmet Baydin
Ondokuz Mayis Üniversitesi, Turkey
Saban Esen
Ondokuz Mayis Üniversitesi, Turkey
Dursun Aygun
Ondokuz Mayis Üniversitesi, Turkey
Murat Hokelek
Ondokuz Mayis Üniversitesi, Turkey
Zahide Doganay
Ondokuz Mayis Üniversitesi, Turkey
Yuksel Bek
Ondokuz Mayis Üniversitesi, Turkey
Özet
Researchers and clinicians have been investigating and implementing various methods of early diagnosis for sepsis before documentation of infection. The aim of this study was to outline the efficiency of procalcitonin (PCT), C-reactive protein (CRP), and white blood cell count (WBC) in determining the early diagnosis of sepsis in the emergency department. Between January 1999 and September 2000, 34 patients with signs of systemic inflammatory response syndrome (SIRS) were enrolled in the study. The patients were divided into 2 groups according to nonsuspected sepsis and suspected sepsis clinically. Admission PCT was significantly higher in suspected sepsis group (median 68.7 μg/L; lower [L] = 15.24 μg/L, upper [U] = 120.54 μg/L) compared with the unsuspected sepsis group (.23 μg/L; L = .10 μg/L, U = .44 μg/L). PCT values were compared with WBC and CRP levels. Predictive accuracy for sepsis expressed as area under the receiver operating characteristic (ROC) curve was .88 for PCT, .44 for WBC, and .34 for CRP. PCT can probably be used as a predictive marker in bacterial infections in emergency departments. Copyright 2002, Elsevier Science (USA). All rights reserved.
Anahtar Kelimeler
C-reactive protein | Emergency departments | Procalcitonin | Sepsis
Makale Türü Özgün Makale
Makale Alt Türü SCOPUS dergilerinde yayımlanan tam makale
Dergi Adı American Journal of Emergency Medicine
Dergi ISSN 0735-6757
Makale Dili İngilizce
Basım Tarihi 01-2002
Cilt No 20
Sayı 3
Sayfalar 202 / 206
Doi Numarası 10.1053/ajem.2002.33005
BM Sürdürülebilir Kalkınma Amaçları
Atıf Sayıları
SCOPUS 68
Diagnostic value of procalcitonin levels as an early indicator of sepsis

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