Administration of midazolam for premedication

Tur, A.; DOĞANAY, Zahide; Yesiltas, F.; Sahinoglu, H.; Ustun, E.; Sarihasan, B.; Guldogus, F.

Administration of midazolam for premedication

Yazarlar (7)

A. Tur
Ondokuz Mayis Üniversitesi, Türkiye

Prof. Dr. Zahide DOĞANAY Ondokuz Mayis Üniversitesi, Türkiye

F. Yesiltas
Ondokuz Mayis Üniversitesi, Türkiye

H. Sahinoglu
Ondokuz Mayis Üniversitesi, Türkiye

E. Ustun
Ondokuz Mayis Üniversitesi, Türkiye

B. Sarihasan
Ondokuz Mayis Üniversitesi, Türkiye

F. Guldogus
Ondokuz Mayis Üniversitesi, Türkiye

Makale Türü	Özgün Makale (SCOPUS dergilerinde yayınlanan tam makale)
Dergi Adı	Ondokuz Mayis Universitesi Tip Dergisi
Dergi ISSN	1300-2996
Makale Dili	İngilizce	Basım Tarihi	12-1997
Cilt / Sayı / Sayfa	14 / 3 / 194–199	DOI	–
UAK Araştırma Alanları	Sağlık Bilimleri

Özet

Applying a conscious premedication provide us appropriate conditions for anesthesia induction and maintenance and preventing the postoperative complications. Benzodiazepins are the most effective group of drugs for this aim. In this study, midazolam one of the benzodiazepine was used for premedication. We investigate the effects of midazolam on mean arterial pressure (MAP), heart rate (HR), respiratory rate (RR), saturation of oxygen (SaO2) and sedation level (SL). Forty patients (ASA I-II) were divided into two groups. Each group implied twenty patients. Group 1 (Midazolam group) were premedicated by 0.07 mg/kg intramuscular midazolam thirty minutes before the operation. Group 2 (Control group) were non-premedicated. MAP and HR were measured before premedication, at induction, after intubation and extubation and than compared these values between two groups. There were no significant differences at MAP, HR values before induction, at induction and maintenance of anesthesia between two groups. The RR of midazolam group was significantly less before induction than before premedication (p <0.05) and sedation level was significantly increased (p < 0.05). In conclusion; premedication with midazolam increased SL, at preoperative and postoperative periods, provided cardiac stability at induction and maintenance of anesthesia. This method can preferred for these reasons.

Anahtar Kelimeler

Benzodiazepine | Midazolam | Premedication

BM Sürdürülebilir Kalkınma Amaçları

Atıf Sayıları

Administration of midazolam for premedication

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