| Yazarlar |
Halit Acet
Dicle Üniversitesi, Turkey |
|
Faruk Ertaş
Dicle Üniversitesi, Turkey |
|
Mehmet Ata Akıl
Dicle Üniversitesi, Turkey |
|
Ferhat Özyurtlu
İzmir Üniversitesi, Turkey |
Prof. Dr. Abdulkadir YILDIZ
Kastamonu Üniversitesi, Türkiye |
|
Nihat Polat
Dicle Üniversitesi, Turkey |
|
Mehmet Zihni Bilik
Dicle Üniversitesi, Turkey |
|
Mesut Aydin
Dicle Üniversitesi, Turkey |
|
Mustafa Oylumlu
Dicle Üniversitesi, Turkey |
|
Hasan Kaya
Dicle Üniversitesi, Turkey |
|
Murat Yüksel
Dicle Üniversitesi, Turkey |
|
Abdurrahman Akyüz
Dicle Üniversitesi, Turkey |
|
Hilal Ayçiçek
Dicle Üniversitesi, Turkey |
|
Sait Alan
Dicle Üniversitesi, Turkey |
|
Nizamettin Toprak
Dicle Üniversitesi, Turkey |
| Özet |
| Objective: The neutrophil/lymphocyte ratio (NLR), the platelet/lymphocyte ratio (PLR), and uric acid (UA) are inflammatory markers in cardiovascular disease. However, there are not enough data on infarct-related artery (IRA) patency in ST-segment elevation myocardial infarction (STEMI). We aimed to investigate the association of NLR, PLR, and UA with IRA patency before percutaneous coronary intervention (PCI) in STEMI. Methods: The study was designed as a retrospective study. Three hundred and twenty-four consecutive patients with STEMI were divided into two groups according to pre-PCI Thrombolysis in Myocardial Infarction flow grade (TIMI). Patients with a TIMI flow grade of into the spontaneous reperfusion (SR) group, while patients with TIMI flow grade of 0, 1 and 2 were placed into the non-SR group. The χ2 and independentsamples t-test, Mann-Whitney U test, multivariate logistic regression analysis, and receiver-operator characteristic (ROC) curve analysis were used for the statistical analysis. Results: PLR, NLR, and UA values in the SR group were lower than in the non-SR group (p<0.004, p<0.001, p<0.001, respectively). In the multivariate analysis, serum UA level and PLR were found to be independent predictors of pre-PCI IRA patency. In the ROC curve analysis, PLR >190, UA>5.75 mg/dL, and NLR>4.2 predicted non-SR. The sensitivity and specificity of the association between low IRA TIMI flow grade and PLR were 88% and 84%, 72% and 66% for UA, and 74% and 44% for NLR, respectively. Conclusion: We determined that PLR and UA are novel predictors of IRA patency before PCI. We suggest that PLR and UA may be used in riskstratifying STEMI. |
| Anahtar Kelimeler |
| Acute myocardial infarction | Coronary angiography | Infarctrelated artery patency | Neutrophil-to-lymphocyte ratio | Platelet-to-lymphocyte ratio | Uric acid |
| Makale Türü | Özgün Makale |
| Makale Alt Türü | SCOPUS dergilerinde yayımlanan tam makale |
| Dergi Adı | Anadolu Kardiyoloji Dergisi |
| Dergi ISSN | 1302-8723 |
| Makale Dili | İngilizce |
| Basım Tarihi | 08-2015 |
| Cilt No | 15 |
| Sayı | 8 |
| Sayfalar | 648 / 656 |
| Doi Numarası | 10.5152/akd.2014.5592 |
| Atıf Sayıları | |
| SCOPUS | 16 |
