Drug Delivery by (5,5) Armchair SWCNT in Bone Tissue through Adsorption of Protein-Bisphosphonate Agents: Metal Chelation Study of Mg2+, Ca2+, Sr2+
Yazarlar (5)
Somayeh Khosravi
Islamic Azad University, Science And Research Branch, İran
Islamic Azad University, Science And Research Branch, İran
Prof. Dr. Majıd MONAJJEMI Islamic Azad University, Central Tehran Branch, İran
Dr. Öğr. Üyesi Fatemeh MOLLAAMIN Kastamonu Üniversitesi, Türkiye
Karim Zare
Islamic Azad University, Science And Research Branch, İran
Islamic Azad University, Science And Research Branch, İran
Masoumeh Sayadian Islamic Azad University, Islamshahr Branch, İran
| Makale Türü | Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale) | ||
| Dergi Adı | Russian Journal of Physical Chemistry A (Q4) | ||
| Dergi ISSN | 0036-0244 Wos Dergi Scopus Dergi | ||
| Dergi Tarandığı Indeksler | |||
| Makale Dili | İngilizce | Basım Tarihi | 05-2023 |
| Cilt / Sayı / Sayfa | 97 / 5 / 1058–1073 | DOI | 10.1134/S0036024423050254 |
| Makale Linki | https://link.springer.com/article/10.1134/s0036024423050254 | ||
| UAK Araştırma Alanları |
Fen Bilimleri ve Matematik
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| Özet |
| Single-walled carbon nanotube (SWCNT) joint to some ligands of bisphosphonate agents including 5AEL, 5AFX, 4QPF, 3DYG, 2F92, 2I19 chelated to metal cations of Mg2+, Ca2+, Sr2+ has been investigated due to the direct electron transfer principle using density functional theory (DFT) methods. Bisphosphonate medications can be applied in prohibition the damage of bone density and the remedy of bone illnesses such as osteoporosis. As the metal chelating of phosphonate groups are nearby large with six O atoms possessing the high negative charge, these compounds are active towards producing the chelated complexes through drug design method. In this work, it has been accomplished the B3LYP/6-311+G(d, p)/LANL2DZ to estimate the susceptibility of SWCNT for adsorbing 5AEL, 5AFX, 4QPF, 3DYG, 2F92, 2I19 chelated to metal cations of Mg2+, Ca2+, Sr2+ through nuclear magnetic resonance and … |
| Anahtar Kelimeler |
| (5,5) armchair SWCNT | 5AEL, 5AFX, 4QPF, 3DYG, 2F92, 2I19 | IR, NMR, DFT | metal chelating | Mg2+, Ca2+, Sr2+ | protein–bisphosphonate |
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları |